Working Memory Limit of Young Male Wistar Rats in Return T Maze Delayed Spontaneous Task Alternation
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 1
Abstract
In rat maze training tasks, the working memory is a short term memory of remembering a previously visited area or reward to solve the task which lasts for a single trial. 10 young (age = 4 months) male Wistar rats were selected to perform delayed spontaneous alternation task in Return T Maze which involves working memory. For each rat, 8 trials are given per day for 15 sec restrain, 30 sec restrain, 45 sec restrain, 60 sec restrain, 75 sec restrain, 90 sec restrain, 105 sec restrain, 120 sec restrain respectively for 10 days (Each day 8 restrain trials x 10 days = 80 trials for each rat). We did not find any preference for the right or left turn during the first spontaneous free choice which excludes the possibilities of presence of attractful cues on a particular side as well as innate nature of a particular rat to turn on the same side repeatedly. Our result shows the range of working memory in between 45-75 seconds, however the rat can continue to solve the task beyond that limit either by simple chance or orientation by their reference memory which is developed from repeated exposure on the maze. This result will help to conduct different maze task which involves working memory.
Authors and Affiliations
Joy Karmakar, Juhi Gupta
Keywords
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