WOUND HEALING ACTIVITY ON THE LEAVES OF ACHILLEA MILLEFOLIUM L. BY EXCISION, INCISION, AND DEAD SPACE MODEL ON ADULT WISTAR ALBINO RATS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 3
Abstract
The aim of present study was to investigate the wound healing activity of the Indian medicinal plant Achillea millefolium L. The alcoholic and aqueous extracts of leaves of Achillea millefolium L was studied for its effect on wound healing in Wistar rats, using incision, excision, and dead space model at dose levels of 200mg/kg. Alcoholic and aqueous extracts of leaves of Achillea millefolium L. showed a definite, positive effect on wound healing with a significant increase in the rate of wound contraction, skin breaking strength, granulation tissue dry weight and wet weight content, and breaking strength of granulation tissue. In histopathological studies showed increased collagen when compared to the control. The efficacy of Achillea millefolium L. in wound healing may be due to the presence of active principles, which accelerate the healing process and confers breaking strength to the healed wound. So it is possible to conclude that, this plant has wound healing activity and there by justifying traditional claim.
Authors and Affiliations
S. Nirmala , T. Karthiyayini
Keywords
Related Articles
- EP ID EP86414
- DOI -
- Views 147
- Downloads 0
ASSESSMENT OF OLIGOSPERMIA WITH SPECIAL REFERENCE TO SHUKRADUSHTI
Diagnosed Patients of Oligospermia were taken for Semen analysis for comparison of Shukradushti with vitiation of Doshas. The assessment of Oligospermia with Ayurvedic Shukradushti was analysed by modern equipment. As pe...
CLINICAL IMPORTANCE OF SUSHRUTOKTA DWADASHAVIDHA PARIKSHA
A patient constitutes karyadesha, that’s why patients should be examined thoroughly to obtain the knowledge of life span, strengths and intensity of morbidity because treatment may be initiated after knowing the intensit...
SIMULTANEOUS ESTIMATION AND VALIDATION OF PARACETAMOL, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE HYDROCHLORIDE, CAFFEINE AND ITS STRESS DEGRADATION STUDIES USING UV VISIBLE SPECTROSCOPY
A simple, precise, accurate and economic simultaneous UV spectrophotometric method has been developed for the estimation of Paracetamol, Chlorpheniramine Maleate, Phenylephrine Hydrochloride and Caffeine in tablet formul...
DEVELOPMENT OF A SIMPLE UV-SPECTROPHOTOMETRIC ASSAY METHOD FOR SATRANIDAZOLE AND STUDY OF ITS DEGRADATION PROFILE
A simple, selective, rapid, precise, economical, reproducible and stability-indicating UV spectrophotometric method has been developed and validated for determination of Satranidazole in pure form and pharmaceutical dosa...
WOUND HEALING ACTIVITY OF ETHANOL EXTRACT OF PSEUDARTHRIA VISCIDA LINN
The wound healing activity of topically applied ethanol extract of Pseudarthria viscida was evaluated in wistar rat by excision wound model for a period of 12 days. The extract was prepared as ointment form (5 and 10% w/...