Wpływ wybranych czynników kliniczno-morfologicznych na wyniki leczenia chorych z zawansowanym rakiem krtani
Journal Title: Otolaryngologia Polska - Year 2013, Vol 67, Issue 1
Abstract
Introduction: The aim of the study was to indicate independent prognostic factors of treatment in group of patients with advanced cancer of the larynx. Material and method: The paper presents results of univariate and multivariate analysis of selected clinical and morphological factors in the group of 355 patients with advanced laryngeal cancer treated in the ENT Clinical Department in Zabrze in the following years 1998–2007. The analysis of the results of treatment in relation to clinical and morphological features of the tumor was based on overall survival, disease-free survival, local control and locoregional control. The results of analysis allowed to indicate the independent prognostic factors for outcome in patients with advanced laryngeal cancer. Results: Univariate analysis showed that the increase of clinical advancement of laryngeal cancer was associated with worse prognosis, as well as the fact that the primary location of the tumor in supraglottis and infiltration in laryngeal part of pharynx determined the worse outcome. Univariate and multivariate analysis confirmed that the number of lymph node metastases in the surgical specimen and microscopic radical of surgery were the most important prognostic factors for survival and cure in the study group. Conclusion: The strongest independent prognostic significance for all efficacy criteria have: completeness of operation and number of metastatic lymph nodes.
Authors and Affiliations
Katarzyna Miśkiewicz-Orczyk, Grzegorz Namysłowski, Maciej Misiołek, Wojciech Majewski
Keywords
Related Articles
- EP ID EP52141
- DOI -
- Views 112
- Downloads 0
XXXIII Zimowy Kongres ARO w Anaheim
-<br/><br/>
Wewnątrzczaszkowe powikłania z zakażeń zatok przynosowych
Wstęp: Zatokopochodne powikłania wewnątrzczaszkowe mimo coraz lepszych metod diagnostycznych i terapeutycznych niezmiennie stanowią stan bezpośredniego zagrożenia życia dla chorych oraz wyzwanie dla otolaryngologów. Cel...
Operacje endoskopowe nosa i zatok przynosowych w materiale własnym
Wstęp<br/><br/>
The problems and question marks in precancerous lesions of the larynx
Background: Development of the laryngeal squamous cell carcinoma is taking place on the base of well-documented precancerous lesions. In histological examination precancerous lesions show dysplasia which may be reversibl...
Laryngologiczny obraz refluksu krtaniowo-gardłowe doświadczenia własne w diagnozowaniu i leczeniu
Introduction: For many years the specialists, have been interested in gastroesophageal reflux. The aim of the work is to present our experience in the diagnosis and the treatment of laryngopharyngeal reflux. Material and...