Wpływ wykonania kochleostomii na zachowanie słuchu – badania na modelu zwierzęcym
Journal Title: Otolaryngologia Polska - Year 2010, Vol 64, Issue 7
Abstract
Introduction: To assess an effect of cochleostomy on hearing threshold in guinea pigs. Material and methods: The authors performed animal experiments using fi ve 3-month-old guinea pigs. Before experiment hearing threshold were evaluated. Surgery involved access to the temporal bone by a post-auricular incision. After a wide opening of the bulla cochleostomy was created (10 000 turn/min, diamond bur of 0,8 mm diameter). Hearing threshold was identifi ed on the basis of presence of wave V in auditory brainstem responses (ABR) for click and frequency-specifi c stimulation. Also morphology and latency changes for wave V for this stimulation was assesed. Hearing status was evaluated before, just after and 1-, 2-, and 4-weeks after surgery. For surgical procedure and ABR examination all animals were anesthetized with an intramuscular injection of ketamine (50 mg/kg) mixed with xylazine (9 mg/kg) in the supplemental doses. After surgery the animal was treated by antibioticoterapy for 3 days – Enrofl oksacyna 0,3 ml subcutaneouly and analgesic – Tolfedine 0,05 mg in second day. Results: Four week observation of ABR morphology and hearing thresholds for click and frequency-specifi c stimulation of 100 dB SPL intensity showed only temporary changes confi rming that cochleostomy did not affect cochlear function. Conclusions: The correctly performed cochleostomy in guinea pigs did not affect persistently the cochlear function indicating that such an option of CI electrode insertion in patients is safe.<br/><br/>
Authors and Affiliations
Olimpia Stanisławek-Sut, Krzysztof Morawski, Kazimierz Niemczyk
Keywords
Related Articles
- EP ID EP345860
- DOI -
- Views 86
- Downloads 0
The impact of vibratory stimulation therapy on voice quality in hyperfunctional occupational dysphonia
SUMMARY Hyperfunctional dysphonia is the most frequent type of occupational functional dysphonia. Pharmacotherapy, physiotherapy and psychotherapy are used in the treatment of occupational dysphonia. Vibratory massages o...
The use of RSI and RFS questionnaires in the Polish language version
RSI and RFS questionnaires are a basic and common method used for initial diagnosis of laryngopharyngeal reflux (LPR). However, they only measure symptoms which may or may not be concurrent with LPR. The severity of thes...
Usefulness of high-speed digital imaging (HSDI) in the diagnosis of oedematous – hypertrophic changes of the larynx in people using voice occupationally
<br/><b>Introduction</b>. The aim of the study is the evaluation of the usefulness of High-Speed Digital Imaging (HSDI) in the diagnosis of organic dysphonia in a form of oedematous-hypertrophic changes of vocal fold muc...
Rzadki przypadek włókniaka układu siateczkowo-śródbłonkowego w przestrzeni przygardłowej u czternastoletniej dziewczynki
The subject of our presentation is the case of a fourteen year old girl with rare histological type of histiocytoma malignum and with rare localisation of the primary neoplasm of the parapharyngeal space. Anatomopatholog...
Zastosowanie noża wodnego ERBEJET 2 w chirurgii ślinianek
Anatomical location of salivary glands requires from surgeon high precision during the operation in this site. Waterjet is one of the modern tools wchich allows to perform „minimal invasive“ operating procedure. This too...