Wrongs known as right in thyroid scintigraphy and uptake study
Journal Title: The European Research Journal - Year 2019, Vol 5, Issue 1
Abstract
Objectives: Thyroid scintigraphy using 99mTc-pertechnetate is commonly used to study function and structure of thyroid gland. Pin-hole collimator is generally preferred in thyroid scintigraphy and uptake studies. The purpose of the present study was to determine actual radiopharmaceutical uptake value in an experimental 99mTc-pertechnetate thyroid scintigraphy and uptake model. Methods: Thyroid hyperactive and hypoactive nodule models were created using 4 mCi (148 MBq) 99mTc-pertechnetate. In the experimental model, 4 mm, 6 mm and 8 mm diameter pin-hole collimators, and 5 cm, 7 cm and 10 cm object-to-pinhole distances were investigated. Results: In thyroid hyperactive nodule model, despite the same activity value, uptake at 7 cm object-to-pinhole distance was higher compared to 10 cm distance (122% and 103%, respectively). In the patient with Graves’ disease, despite the same activity value, uptake at 5 cm object-to-pinhole distance was higher compared to 10 cm distance (8% and 4%, respectively). In thyroid hypoactive nodule model, 4 mm, 6 mm and 8 mm diameters pin-hole collimators were imaged at 5 cm, 10 cm and 15 cm object-to-pinhole distances. The resolution differences between the images were evaluated. Conclusion: It was determined that imaging using 10 cm object-to-pinhole distanceand 4 mm diameter pin-hole collimator was best in terms of image resolution and optimum 99mTc-pertechnetate uptake level.
Authors and Affiliations
Serdar Savaş Gül
Keywords
Related Articles
- EP ID EP491577
- DOI 10.18621/eurj.410060
- Views 65
- Downloads 0
Acute pancreatitis and type 2 diabetes mellitus: who is guilty?
Many factors play a role in the etiology of acute pancreatitis and its pathogenesis is not fully understood. Dipeptidyl peptidase 4 (DPP-4) inhibitors are a new group of agents for the treatment of Diabetes Mellitus (DM)...
The frequency of toll-like receptor 4 gene polymorphism in ankylosing spondylitis and its relationship between disease activity
Objectives. We aimed to evaluate the frequency of toll-like receptor 4 (TLR4) gene polymorphism and its relationship between disease activity in patients with ankylosing spondylitis (AS). Methods. Forty-one AS patients (...
Preoperative hemogram-related parameters to distinguish renal cell carcinoma from benign kidney masses: HERR score
Objectives: Renal cell carcinoma (RCC) accounts for approximately 90% of all kidney malignancies, and it is difficult to preoperatively distinguish between tumors and benign masses without a kidney biopsy in small renal...
Can QT dispersion predict multi-vessel coronary artery disease in patients with acute coronary syndrome?
Objective. This study was planned to evaluate relation between QT dispersion (QTd) and multi-vessel coronary artery disease in acute coronary syndrome. Methods. This study included 225 consecutive patients with a diagnos...
Primary cardiac B-cell lymphoma
Primary tumors of the heart are very uncommon and approximately 25% of them are malign. Primary cardiac lymphomas account for approximately 4% of the primary cardiac tumors. Both B- and T-cell lymphomas have been reporte...