Wrongs known as right in thyroid scintigraphy and uptake study
Journal Title: The European Research Journal - Year 2019, Vol 5, Issue 1
Abstract
Objectives: Thyroid scintigraphy using 99mTc-pertechnetate is commonly used to study function and structure of thyroid gland. Pin-hole collimator is generally preferred in thyroid scintigraphy and uptake studies. The purpose of the present study was to determine actual radiopharmaceutical uptake value in an experimental 99mTc-pertechnetate thyroid scintigraphy and uptake model. Methods: Thyroid hyperactive and hypoactive nodule models were created using 4 mCi (148 MBq) 99mTc-pertechnetate. In the experimental model, 4 mm, 6 mm and 8 mm diameter pin-hole collimators, and 5 cm, 7 cm and 10 cm object-to-pinhole distances were investigated. Results: In thyroid hyperactive nodule model, despite the same activity value, uptake at 7 cm object-to-pinhole distance was higher compared to 10 cm distance (122% and 103%, respectively). In the patient with Graves’ disease, despite the same activity value, uptake at 5 cm object-to-pinhole distance was higher compared to 10 cm distance (8% and 4%, respectively). In thyroid hypoactive nodule model, 4 mm, 6 mm and 8 mm diameters pin-hole collimators were imaged at 5 cm, 10 cm and 15 cm object-to-pinhole distances. The resolution differences between the images were evaluated. Conclusion: It was determined that imaging using 10 cm object-to-pinhole distanceand 4 mm diameter pin-hole collimator was best in terms of image resolution and optimum 99mTc-pertechnetate uptake level.
Authors and Affiliations
Serdar Savaş Gül
Keywords
Related Articles
- EP ID EP491577
- DOI 10.18621/eurj.410060
- Views 90
- Downloads 0
Family history in developmental dysplasia of the hip: should we follow-up?
Objectives: Developmental dysplasia of the hip (DDH) is an important problem. Ultrasonography (US) is a proper method before 6 months of age. For older children, plain radiographs can be useful. Six risk factors are emph...
Incidence and risk factors of contrast-induced nephropathy after diagnostic or interventional coronary angiography
Objectives. Contrast-induced nephropathy (CIN) is the third most common cause of acute renal failure that occurred in the hospital. In Turkey, there is not enough data about the frequency of CIN in cardiological interven...
Acute pancreatitis and type 2 diabetes mellitus: who is guilty?
Many factors play a role in the etiology of acute pancreatitis and its pathogenesis is not fully understood. Dipeptidyl peptidase 4 (DPP-4) inhibitors are a new group of agents for the treatment of Diabetes Mellitus (DM)...
Inlay butterfly cartilage tympanoplasty for large central perforations
Objective. The aim of this study is to evaluate the results of inlay butterfly tympanoplasty technique in large central tympanic membrane perforations. Methods. The files of the patients who underwent inlay butterfly car...
Evaluation of high molecular weight cytokeratin (HMWCK), p27, C-X-C chemokine receptor type 4 (CXCR-4) and stromal cell-derived factor 1 (SDF-1) expressions related to tumor progression in breast cancer
Objectives: Breast cancer is the most common cancer and the most common reason for cancer death in women population. The immunohistochemical markers which could have prognostic information are always needed. Methods: Th...