YELLOW FEVER VIRUS (YFV) INFECTION EVALUATION USING RAPID DIAGNOSTIC TESTS (RDTS) BASED ON ANTI-YFV IGM/IGG
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 5
Abstract
Yellow fever (YF) is an acute viral haemorrhagic disease transmitted by infected genus Aedes mosquitoes. The yellow fever virus (YFV) is mostly found in tropical and subtropical areas of Africa and South America. Outbreaks recently reached considerable proportions in terms of spatial distribution and total numbers of cases, with multiple exports, including to China. There is no medicine to treat or cure infection. Rapid diagnostic tests (RDTs) for the detection of YFV antigens are based on the immunochromatographic test principle. A total of 124 prospective serum samples submitted for yellow fever virus (YFV) IgM and IgG testing. All 124 serum samples among 124 in Brazil showed IgG positive results with YFV. Thus sensitivity of the GenBody Company RDT was 100.0% for IgG. 11 samples among 12 were negative. Specificity of GenBody kits was 91.6% (11/12) for YFV. It is suggested that the rapid diagnosis kit of GenBody -company can be used as a useful test for Yellow fever virus management.
Authors and Affiliations
Yong Lim
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