YELLOW PHOSPHOROUS POISONING: AN OBSERVATIONAL STUDY FROM A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 12
Abstract
BACKGROUND Yellow phosphorous, a rodenticide, is a lethal toxin in humans that can cause damages to hepatic, cardiovascular, gastrointestinal and the renal systems and it carries significant morbidity and mortality. The current study evaluated the mortality, outcomes and complications associated with acute yellow Phosphorous poisoning. MATERIALS AND METHODS The retrospective study was conducted at a teaching hospital in South India, between January 2015 and March 2017. Subjects >13 years of age with acute poisoning due to 3% yellow phosphorous were included in the study. They were classified into various groups based on age, gender, the amount consumed, and time delays in receiving hospital care. The various outcomes including the incidence in different age groups, amount of poison consumed, proportion of patients died, and proportion of patients cured were analysed. Statistical analyses were performed using GraphPad Prism 5.0. RESULTS The study enrolled a total of 334 cases, and the male-to-female ratio noted was 0.94:1. Majority of the subjects belonged to the age group of 20-29 years. A mortality rate of 76.24% was observed among the subjects with known outcomes. The complications noted in the subjects included toxic hepatitis, clinical jaundice, hepatic encephalopathy, hypoglycaemia, myocarditis, bleeding, respiratory failure and shock. Highest rate of survival was noted in the group treated with N-acetyl cysteine. CONCLUSION The study further corroborates the increased incidence of mortality, due to the unavailability of appropriate antidote to yellow Phosphorous. Additionally, increased incidence of self-poisoning was noted in younger age group.
Authors and Affiliations
Vinoth Appavu, Deborah Anthirias, Haripriya Dhanaraj, Mageshwaran Lakshmanan, Sujitha Ananthakumar, Swathi J. P. K, Swathy Vinayagam, Chouthri Sekar
Keywords
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- EP ID EP615669
- DOI 10.18410/jebmh/2019/208
- Views 110
- Downloads 0
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