Yield of bone marrow evaluation in outpatients with neutropenia
Journal Title: International Journal of Medical and Health Research - Year 2018, Vol 4, Issue 3
Abstract
Introduction and Research Problem: Establishing the cause of neutropenia in outpatients can be challanging. Thorough clinical and labortaoy evaluation are required. The yield of assessment of the bone marrow (BM) through BM aspiration and biopsy is not clear. Materials and Methods: In this retrosepctive chart review investigators reviewed records of all patients who underwent BM assessment in King Adulaziz University Hospital between 1 January 2004 - 31 August 2015 and identfied outpatients who underwent the procedure for investigation of isolated neutropenia or with associated thrombocytoepnia and/or anemia. Summary of Results: Among 2590 BM assessment procedures, 36 patients underwent the procedure for workup of neutropenia. 5 patients had isolated neutropenia and BM in these patients was either normal or showed mild hypocellulairty. In the 31 remaining patients with neutropenia assoicated with anemia and/or thrombocytopenia, various diseases were identified in BM such as leukemia and myelofibrosis. Conclusion and Recommendations: None of the patients who had BM assessemnt for isolated neutropenia were found to have a hematologcial malignancy. However,the small sample size does not allow investigators to draw any generlizable conclusions.
Authors and Affiliations
Maha Badawi, Maram Althagaf, Reema Shabkah, Fayeza Alam
Keywords
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