Zika virus fever: beginning of another Zoonotic dilemma?
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
In 2016,World Health Organization (WHO) declared a Public Health Emergency due to the recent outbreak of Zika fever in Brazil.Zika virus is a mosquito-borne flavivirus related to dengue virus. Infection can also spread by sexual transmission from infected men. Cases of vertical perinatal transmission have been reported, with multiple problems, including microcephaly, and chorioretinal scaring.Zika virus infections have been associated with Guillain –Barre syndrome (GBS), damaging the peripheral nervous system, which can progress to paralysis. Symptoms of Zika fever are fever, rash, conjunctivitis, muscle and joint pain, and headache, similar to dengue and chikungunya fever Differential diagnosis of Zika fever should exclude other infection including denguechikungunya ,leptospirosis,malaria,group A streptococcus,rubella,measles,parvovirus,enterovirus,adenovirus,and alphavirus infection, and other viruses. Pregnantwomen living in the affected areas, theCDC has recommended testing at first perinatal visit and in the mid-second trimester. At present there is no specific treatment for Zika virus infection, care is only supportive. Use of aspirin and other NSAIDs use is generally avoided as these are associated with hemorrhagic syndrome, especially in children due to the risk of Reye syndrome. The CDC strategies for controlling mosquitoes are useful. Currently there is no available vaccine. To speed new drug development has been proposed by the WHO and NIH.
Authors and Affiliations
Murtaza Mustafa, IM. Yusof, AM, Sharifa, EM. Illzam, RK. Muniandy, K. Fairrul, H. Firdaus, MK. Nang
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