Zinc concentrations in the expressed prostatic fluid of patients with bladder cancer
Journal Title: Iberoamerican Journal of Medicine - Year 2020, Vol 2, Issue 3
Abstract
Introduction: In our previous studies it was concluded that the zinc (Zn) level in in human expressed prostatic fluid (EPF) is a first candidate with the role of offering a new, simple, fast, reliable, and non-invasive diagnostic tool for prostate cancer (PCa) screening. However it was unclear how other non-prostatic diseases inherent of the old persons, including heart diseases, atherosclerosis, diabetes, asymptomatic cancer of different localization and some others, impact on a chemical element composition of expressed prostatic fluid. Thus, the purpose of this study was to evaluate whether significant changes in the levels of Zn in EPF exist in patients with bladder cancer (BC). Methods: Prostatic fluid levels of Zn were prospectively evaluated in 17 patients with BC and 51 healthy male inhabitants (control group). Measurements were performed using 109Cd radionuclide-induced energy dispersive X-ray fluorescent microanalysis developed by us. Results: Mean value standard deviation of mean (MSD) for concentration of Zn in the EPF of healthy males and patients with BC was 573202 mg/L and 625±108 mg/L, respectively. Using both parametric Student’s t-test and non-parametric Wilcoxon-Mann-Whitney U-test it was shown that the Zn concentration in the EPF of patients with BC did not differ from that in healthy subjects. Conclusion: Such serious illness as BC did not impact on the Zn concentration in the EPF.
Authors and Affiliations
Vladimir Zaichick, Sofia Zaichick
Keywords
Related Articles
- EP ID EP684601
- DOI https://doi.org/10.5281/zenodo.3786267
- Views 155
- Downloads 0
Polycystic Liver Disease – Something to Consider in Case of an Acute Abdomen
..........
Coexistence of central precocious puberty and intraventricular arachnoid cyst: a brief literature update
Central precocious puberty (CPP) is a rare disease. The mean annual incidence in girls is 0.8-1.1/100,000 and in boys 0-0.1/100,000. Intracranial arachnoid cysts (ICACs) are usually congenital and represent 1% of intracr...
The case of missing punctum
We report a case of a 25-year-old male with a long history of watering from both the eyes. Complete ocular examination of the patient was carried out under slit lamp. Out of four, three punctums were found absent in our...
Banana fibers camouflaging as a gut worm in a 6-month-old infant
Worm infestation issue is a common health condition observed mostly in Asian countries. The prevalence of worms in children is higher due to the habit of playing in mud or outdoors which is not found in the case of an in...
A Systematic Review of the Calcium Content of the Normal Human Prostate Gland
Introduction: There is much lack of knowledge concerning most prostatic malfunction, especially the reasons and detailed nature of its pathologies. In spite of advances in medical science, the differential diagnosis of p...