ZINC PEROXIDE NANOPARTICLES: PROMISING SOURCE COMBATING CHICKEN MEAT-CONTAINING PATHOGENS
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 10
Abstract
Due to the increase of the chicken meat consumption, the ensuring of microbial safety is essential. Therefore, our study aims to assess the microbiological quality of retailed chickens in local markets at El-Sharkia Governorate, Egypt. Besides, investigating zinc peroxide nanoparticles (ZnO2-NPs) antibacterial activity against pan drug-resistant bacteria (PDR). For this purpose, an Antibiotic susceptibility test was performed using 10 different antibiotics to detect MDR and PDR bacteria in retail chicken meat cuts-up. All PDR bacteria were selected and identified using 16S rRNA. Also, the activity of ZnO2-NPs was investigated against PDR isolates. Our results showed that the average total viable count (TVC) of fresh, chilled and frozen meat estimated by 6.84, 3.75 and 2.1 log10 CFU/g, respectively. The antibacterial susceptibility test revealed that 70% (84/124) of all bacterial isolates were MDR bacteria. Out of these isolates 5 PDR isolates were detected and identified as Pseudomonas aeruginosa IMD85, Escherichia coli O157:H7 and Salmonella enterica ATCC 8387, Staphylococcus aureus 191 and Staphylococcus epidermidis BGHMC11. The antibacterial susceptibility test of ZnO2.NPs against these PDR isolates showed an outstanding activity at different concentrations (50, 100, 150 and 200 μg/ml). The MIC value for the PDR bacterial isolates ranged from 25-150 μg/ml and MBC value ranged from 50-300 μg/ml. ZnO2-NPs have exhibited efficiency as an active antibacterial agent against PDR pathogens suggesting that the ZnO2-NPs are potentially valued for food safety applications.
Authors and Affiliations
Esraa A. Abdelkrim
Keywords
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- EP ID EP674593
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