Ligand Binding Assays in the 21st Century Laboratory: Platforms Journal title: The AAPS Journal Authors: Franklin P. Spriggs, Zhandong Don Zhong, Afshin Safavi, Darshana Jani, Narasaiah Dontha, Anita Kant,... Subject(s): Medicine
Ligand Binding Assays in the 21st Century Laboratory: Automation Journal title: The AAPS Journal Authors: Ago B. Ahene, Chris Morrow, David Rusnak, Susan Spitz, Joel Usansky, Holger Pils, Francesca Civoli,... Subject(s): Medicine
Ligand Binding Assays in the 21st Century Laboratory: Recommendations for Characterization and Supply of Critical Reagents Journal title: The AAPS Journal Authors: Denise M. O’Hara, Valerie Theobald, Adrienne Clements Egan, Joel Usansky, Murli Krishna, Jul... Subject(s): Medicine
Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development Journal title: The AAPS Journal Authors: Jean W. Lee, Marian Kelley, Lindsay E. King, Jihong Yang, Hossein Salimi-Moosavi, Meina T. Tang, Jia... Subject(s): Medicine
Ligand-Binding Mass Spectrometry to Study Biotransformation of Fusion Protein Drugs and Guide Immunoassay Development: Strategic Approach and Application to Peptibodies Targeting the Thrombopoietin Receptor Journal title: The AAPS Journal Authors: Michael P. Hall, Colin Gegg, Kenneth Walker, Christopher Spahr, Robert Ortiz, Vimal Patel, Steven Yu... Subject(s): Medicine
Best practices during bioanalytical method validation for the characterization of assay reagents and the evaluation of analyte stability in assay standards, quality controls, and study samples Journal title: The AAPS Journal Authors: William Nowatzke, Eric Woolf Subject(s): Medicine
Critical ligand binding reagent preparation/selection: When specificity depends on reagents Journal title: The AAPS Journal Authors: Bonita Rup, Denise O'Hara Subject(s): Medicine
Key elements of bioanalytical method validation for macromolecules Journal title: The AAPS Journal Authors: Marian Kelley, Binodh DeSilva Subject(s): Medicine
Appropriate calibration curve fitting in ligand binding assays Journal title: The AAPS Journal Authors: John W. A. Findlay, Robert F. Dillard Subject(s): Medicine
Opioid ligands with mixed μ/δ opioid receptor interactions: An emerging approach to novel analgesics Journal title: The AAPS Journal Authors: Subramaniam Ananthan Subject(s): Medicine
Ligand Binding Assay Critical Reagents and Their Stability: Recommendations and Best Practices from the Global Bioanalysis Consortium Harmonization Team Journal title: The AAPS Journal Authors: Lindsay E. King, Esme Farley, Mami Imazato, Jeannine Keefe, Masood Khan, Mark Ma, K. Susanne Pihl, P... Subject(s): Medicine
Systematic Verification of Bioanalytical Similarity Between a Biosimilar and a Reference Biotherapeutic: Committee Recommendations for the Development and Validation of a Single Ligand-Binding Assay to Support Pharmacokinetic Assessments Journal title: The AAPS Journal Authors: Joseph C. Marini, Michael Anderson, Xiao-Yan Cai, John Chappell, Todd Coffey, Dominique Gouty, Aparn... Subject(s): Medicine
Next Generation Ligand Binding Assays—Review of Emerging Technologies’ Capabilities to Enhance Throughput and Multiplexing Journal title: The AAPS Journal Authors: Johanna Mora, Allison Given Chunyk, Mark Dysinger, Shobha Purushothama, Claude Ricks, Karolina �... Subject(s): Medicine
Evaluation of Acoustic Membrane Microparticle (AMMP) Technology for a Sensitive Ligand Binding Assay to Support Pharmacokinetic Determinations of a Biotherapeutic Journal title: The AAPS Journal Authors: Shannon D. Chilewski, W. Matthew Dickerson, Johanna R. Mora, Ashley Saab, Edward M. Alderman Subject(s): Medicine
Specific Method Validation and Sample Analysis Approaches for Biocomparability Studies of Denosumab Addressing Method and Manufacture Site Changes Journal title: The AAPS Journal Authors: Ramak Pourvasei, Ed Lee, Michael Eschenberg, Vimal Patel, Chris Macaraeg, Kinnari Pandya, Judy Shih,... Subject(s): Medicine