Translating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption Journal title: The AAPS Journal Authors: Andrés Olivares-Morales, Hans Lennernäs, Leon Aarons, Amin Rostami-Hodjegan Subject(s): Medicine
Application of Absorption Modeling in Rational Design of Drug Product Under Quality-by-Design Paradigm Journal title: The AAPS Journal Authors: Filippos Kesisoglou, Amitava Mitra Subject(s): Medicine
Drug Delivery Approaches in Addressing Clinical Pharmacology-Related Issues: Opportunities and Challenges Journal title: The AAPS Journal Authors: Hong Wen, Huijeong Jung, Xuhong Li Subject(s): Medicine
Assessment of In Vivo Clinical Product Performance of a Weak Basic Drug by Integration of In Vitro Dissolution Tests and Physiologically Based Absorption Modeling Journal title: The AAPS Journal Authors: Xuan Ding, Ivelina Gueorguieva, James A. Wesley, Lee J. Burns, Carrie A. Coutant Subject(s): Medicine
Region-Dependent Role of Cell-Penetrating Peptides in Insulin Absorption Across the Rat Small Intestinal Membrane Journal title: The AAPS Journal Authors: El-Sayed Khafagy, Ruisha Iwamae, Noriyasu Kamei, Mariko Takeda-Morishita Subject(s): Medicine
Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate Journal title: The AAPS Journal Authors: Filippos Kesisoglou, Binfeng Xia, Nancy G. B. Agrawal Subject(s): Medicine
The Twofold Advantage of the Amorphous Form as an Oral Drug Delivery Practice for Lipophilic Compounds: Increased Apparent Solubility and Drug Flux Through the Intestinal Membrane Journal title: The AAPS Journal Authors: Arik Dahan, Avital Beig, Viktoriya Ioffe-Dahan, Riad Agbaria, Jonathan M Miller Subject(s): Medicine
Regional-Dependent Intestinal Permeability and BCS Classification: Elucidation of pH-Related Complexity in Rats Using Pseudoephedrine Journal title: The AAPS Journal Authors: Moran Fairstein, Rotem Swissa, Arik Dahan Subject(s): Medicine
Dose Selection Based on Physiologically Based Pharmacokinetic (PBPK) Approaches Journal title: The AAPS Journal Authors: Hannah M. Jones, Kapil Mayawala, Patrick Poulin Subject(s): Medicine
Incorporation of Physiologically Based Pharmacokinetic Modeling in the Evaluation of Solubility Requirements for the Salt Selection Process: A Case Study Using Phenytoin Journal title: The AAPS Journal Authors: Po-Chang Chiang, Harvey Wong Subject(s): Medicine
Impact of Osmotically Active Excipients on Bioavailability and Bioequivalence of BCS Class III Drugs Journal title: The AAPS Journal Authors: Mei-Ling Chen, Nakissa Sadrieh, Lawrence Yu Subject(s): Medicine
Comparison of Intestinal Absorption and Disposition of Structurally Similar Bioactive Flavones in Radix Scutellariae Journal title: The AAPS Journal Authors: Chenrui Li, Li Zhang, Limin Zhou, Siu Kwan Wo, Ge Lin, Zhong Zuo Subject(s): Medicine
Absorption Enhancers: Applications and Advances Journal title: The AAPS Journal Authors: Bruce J. Aungst Subject(s): Medicine
A mechanism-Based Approach for Absorption Modeling: The Gastro-Intestinal Transit Time (GITT) Model Journal title: The AAPS Journal Authors: Emilie Hénin, Martin Bergstrand, Joseph F. Standing, Mats O. Karlsson Subject(s): Medicine
The Solubility–Permeability Interplay and Its Implications in Formulation Design and Development for Poorly Soluble Drugs Journal title: The AAPS Journal Authors: Arik Dahan, Jonathan M. Miller Subject(s): Medicine
