Incorporation of Physiologically Based Pharmacokinetic Modeling in the Evaluation of Solubility Requirements for the Salt Selection Process: A Case Study Using Phenytoin
Journal Title: The AAPS Journal - Year 2013, Vol 15, Issue 4
Abstract
The online version of this article (doi:10.1208/s12248-013-9519-x) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Po-Chang Chiang, Harvey Wong
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Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group
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The human intestinal proton-coupled peptide transporter, hPEPT1 (SLC15A1), has been identified as an absorptive transporter for both drug substances and prodrugs. An understanding of the prerequisites for transport has s...
Model-Based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor
The online version of this article (doi:10.1208/s12248-011-9254-0) contains supplementary material, which is available to authorized users.