Inter-individual variability in propofol pharmacokinetic/pharmacodynamic (PK/PD) model – A sensitivity analysis Journal title: Scholars Journal of Applied Medical Sciences Authors: J. J. Chang, S. Syafiie, Raja Kamil, T. A. Lim Subject(s):
Platelet Dynamics in Peritoneal Carcinomatosis Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Oxaliplatin Journal title: The AAPS Journal Authors: Carlos Pérez-Ruixo, Belén Valenzuela, José Esteban Peris, Pedro Bretcha-Boix... Subject(s): Medicine
Development of a Tumour Growth Inhibition Model to Elucidate the Effects of Ritonavir on Intratumoural Metabolism and Anti-tumour Effect of Docetaxel in a Mouse Model for Hereditary Breast Cancer Journal title: The AAPS Journal Authors: Huixin Yu, Jeroen J. M. A. Hendrikx, Sven Rottenberg, Jan H. M. Schellens, Jos H. Beijnen, Alwin D.... Subject(s): Medicine
Preclinical Pharmacokinetic/Pharmacodynamic Modeling and Simulation in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape Journal title: The AAPS Journal Authors: Edgar Schuck, Tonika Bohnert, Arijit Chakravarty, Valeriu Damian-Iordache, Christopher Gibson, Cheng... Subject(s): Medicine
Population Pharmacodynamic Modeling of Hyperglycemic Clamp and Meal Tolerance Tests in Patients with Type 2 Diabetes Mellitus Journal title: The AAPS Journal Authors: Ying Hong, Jasper Dingemanse, Patricia Sidharta, Donald E. Mager Subject(s): Medicine
Pharmacodynamic Modeling of Sequence-Dependent Antitumor Activity of Insulin-like Growth Factor Blockade and Gemcitabine Journal title: The AAPS Journal Authors: Amit Khatri, Richard C. Brundage, Jessica M. Hull, Brent W. Williams, Douglas Yee, Mark N. Kirstein Subject(s): Medicine
Semi-mechanistic Modeling of the Interaction Between the Central and Peripheral Effects in the Antinociceptive Response to Lumiracoxib in Rats Journal title: The AAPS Journal Authors: Nieves Vélez de Mendizábal, Dalia Vásquez-Bahena, Juan M. Jiménez-An... Subject(s): Medicine
The Pharmacokinetic/Pharmacodynamic Pipeline: Translating Anticancer Drug Pharmacology to the Clinic Journal title: The AAPS Journal Authors: Qingyu Zhou, James M. Gallo Subject(s): Medicine
From Target Selection to the Minimum Acceptable Biological Effect Level for Human Study: Use of Mechanism-based PK/PD Modeling to Design Safe and Efficacious Biologics Journal title: The AAPS Journal Authors: Jing Yu, Helene Karcher, Adam L. Feire, Philip J. Lowe Subject(s): Medicine
Development of a New Pre- and Post-Processing Tool (SADAPT-TRAN) for Nonlinear Mixed-Effects Modeling in S-ADAPT Journal title: The AAPS Journal Authors: Jurgen Bernd Bulitta, Ayhan Bingölbali, Beom Soo Shin, Cornelia Barbara Landersdorfer Subject(s): Medicine
Performance and Robustness of the Monte Carlo Importance Sampling Algorithm Using Parallelized S-ADAPT for Basic and Complex Mechanistic Models Journal title: The AAPS Journal Authors: Jurgen B. Bulitta, Cornelia B. Landersdorfer Subject(s): Medicine
A Flexible Nonlinear Feedback System That Captures Diverse Patterns of Adaptation and Rebound Journal title: The AAPS Journal Authors: Johan Gabrielsson, Lambertus A. Peletier Subject(s): Medicine
Making the Most of Clinical Data: Reviewing the Role of Pharmacokinetic-Pharmacodynamic Models of Anti-malarial Drugs Journal title: The AAPS Journal Authors: Julie A. Simpson, Sophie Zaloumis, Alysha M. DeLivera, Ric N. Price, James M McCaw Subject(s): Medicine
Target-Mediated Disposition Model Describing the Dynamics of IL12 and IFNγ after Administration of a Mifepristone-Inducible Adenoviral Vector for IL-12 Expression in Mice Journal title: The AAPS Journal Authors: Zinnia Patricia Parra-Guillen, Alvaro Janda, Pilar Alzuguren, Pedro Berraondo, Ruben Hernandez-Alcoc... Subject(s): Medicine
Evidence of effectiveness: How much can we extrapolate from existing studies? Journal title: The AAPS Journal Authors: Howard Lee, Dong-Seok Yim, Honghui Zhou, Carl C. Peck Subject(s): Medicine
