Pharmacodynamic Modeling of Sequence-Dependent Antitumor Activity of Insulin-like Growth Factor Blockade and Gemcitabine
Journal Title: The AAPS Journal - Year 2012, Vol 14, Issue 1
Abstract
The online version of this article (doi:10.1208/s12248-011-9308-3) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Amit Khatri, Richard C. Brundage, Jessica M. Hull, Brent W. Williams, Douglas Yee, Mark N. Kirstein
Keywords
Related Articles
- EP ID EP681183
- DOI 10.1208/s12248-011-9308-3
- Views 90
- Downloads 0
Regulation of Generic Drugs in Japan: the Current Situation and Future Prospects
Generic drugs are interchangeable with original proprietary drugs, as they have the same active pharmaceutical ingredients, dosage forms, strength, quality, indications, effects, directions, and dosage. The cost of gener...
Therapeutic Paint of Cidofovir/Sucralfate Gel Combination Topically Administered by Spraying for Treatment of orf virus Infections
The aim of the research was to study a new cidofovir/sucralfate drug product to be used as a spray for treating the mucosal and/or skin lesions. The product, i.e., a water suspension of sucralfate (15% w/w) and cidofovir...
A Fast Method for Testing Covariates in Population PK/PD Models
The development of covariate models within the population modeling program like NONMEM is generally a time-consuming and non-trivial task. In this study, a fast procedure to approximate the change in objective function v...
A guide for reporting the results of population pharmacokinetic analyses: A Swedish perspective
Population pharmacokinetic analyses are frequently part of regulatory submissions and are mainly used to provide information on special populations (effects of age, renal impairment, etc) and drug-drug interactions. A va...
Corrigendum: 2007 highlights of advances in the pharmaceutical sciences: An American Association of Pharmaceutical Scientists (AAPS) perspective