Pharmacodynamic Modeling of Sequence-Dependent Antitumor Activity of Insulin-like Growth Factor Blockade and Gemcitabine
Journal Title: The AAPS Journal - Year 2012, Vol 14, Issue 1
Abstract
The online version of this article (doi:10.1208/s12248-011-9308-3) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Amit Khatri, Richard C. Brundage, Jessica M. Hull, Brent W. Williams, Douglas Yee, Mark N. Kirstein
Structural and Activity Profile Relationships Between Drug Scaffolds
The online version of this article (doi:10.1208/s12248-015-9737-5) contains supplementary material, which is available to authorized users.
Animal Models of Osteoarthritis: Challenges of Model Selection and Analysis
Osteoarthritis (OA) is the most common musculoskeletal disease, affecting millions of individuals worldwide. New treatment approaches require an understanding of the pathophysiology of OA and its biomechanical, inflammat...
Workshop Report: Crystal City V—Quantitative Bioanalytical Method Validation and Implementation: The 2013 Revised FDA Guidance
In September 2013, the FDA released a draft revision of the Bioanalytical Method Validation (BMV) Guidance, which included a number of changes to the expectations for bioanalysis, most notably the inclusion of biomarker...
Evaluation of Agile Designs in First-in-Human (FIH) Trials—A Simulation Study
The online version of this article (doi:10.1208/s12248-009-9141-0) contains supplementary material, which is available to authorized users.
A Priori Identifiability of Target-Mediated Drug Disposition Models and Approximations
The online version of this article (doi:10.1208/s12248-015-9795-8) contains supplementary material, which is available to authorized users.