Target-Mediated Disposition Model Describing the Dynamics of IL12 and IFNγ after Administration of a Mifepristone-Inducible Adenoviral Vector for IL-12 Expression in Mice Journal title: The AAPS Journal Authors: Zinnia Patricia Parra-Guillen, Alvaro Janda, Pilar Alzuguren, Pedro Berraondo, Ruben Hernandez-Alcoc... Subject(s): Medicine
Integrated Pharmacokinetic-Driven Approach to Screen Candidate Anticancer Drugs for Brain Tumor Chemotherapy Journal title: The AAPS Journal Authors: Hua Lv, Xiaoping Zhang, Jyoti Sharma, M. V. Ramana Reddy, E. Premkumar Reddy, James M. Gallo Subject(s): Medicine
The Utility of Modeling and Simulation Approaches to Evaluate Immunogenicity Effect on the Therapeutic Protein Pharmacokinetics Journal title: The AAPS Journal Authors: Juan Jose Perez Ruixo, Peiming Ma, Andrew T. Chow Subject(s): Medicine
Pharmacokinetics and bioavailability of the isoflavone biochanin A in rats Journal title: The AAPS Journal Authors: Young Jin Moon, Kazuko Sagawa, Kosea Frederick, Shuzhong Zhang, Marilyn E. Morris Subject(s): Medicine
Rapid in vivo oral screening in rats: Reliability, acceptance criteria, and filtering efficiency Journal title: The AAPS Journal Authors: Hong Mei, Walter Korfmacher, Richard Morrison Subject(s): Medicine
Fish drug analysis—Phish-pharm: A searchable database of pharmacokinetics data in fish Journal title: The AAPS Journal Authors: Renate Reimschuessel, Leslie Stewart, Elizabeth Squibb, Keiko Hirokawa, Tiffany Brady, Deborah Brook... Subject(s): Medicine
A pragmatic approach to the design of population pharmacokinetic studies Journal title: The AAPS Journal Authors: Amit Roy, Ene I. Ette Subject(s): Medicine
Evidence of effectiveness: How much can we extrapolate from existing studies? Journal title: The AAPS Journal Authors: Howard Lee, Dong-Seok Yim, Honghui Zhou, Carl C. Peck Subject(s): Medicine
Population pharmacokinetic studies in pediatrics: Issues in design and analysis Journal title: The AAPS Journal Authors: Bernd Meibohm, Stephanie Läer, John C. Panetta, Jeffrey S. Barrett Subject(s): Medicine
Toward the prediction of CNS drug-effect profiles in physiological and pathological conditions using microdialysis and mechanism-based pharmacokinetic-pharmacodynamic modeling Journal title: The AAPS Journal Authors: Elizabeth C. M. de Lange, Paulien G. M. Ravenstijn, Dorien Groenendaal, Tamara J. van Steeg Subject(s): Medicine
Pharmacokinetics/pharmacodynamics and the stages of drug development: Role of modeling and simulation Journal title: The AAPS Journal Authors: Jenny Y. Chien, Stuart Friedrich, Michael A. Heathman, Dinesh P. de Alwis, Vikram Sinha Subject(s): Medicine
Lung microdialysis—A powerful tool for the determination of exogenous and endogenous compounds in the lower respiratory tract (mini-review) Journal title: The AAPS Journal Authors: Markus Zeitlinger, Markus Müller, Christian Joukhadar Subject(s): Medicine
Pharmacokinetic-pharmacodynamic modeling in the data analysis and interpretation of drug-induced QT/QTc prolongation Journal title: The AAPS Journal Authors: Vladimir Piotrovsky Subject(s): Medicine
Simultaneous population optimal design for pharmacokinetic-pharmacodynamic experiments Journal title: The AAPS Journal Authors: Andrew Hooker, Paolo Vicini Subject(s): Medicine
In vivo microdialysis for PK and PD studies of anticancer drugs Journal title: The AAPS Journal Authors: Qingyu Zhou, James M. Gallo Subject(s): Medicine