Determination of Cellular Processing Rates for a Trastuzumab-Maytansinoid Antibody-Drug Conjugate (ADC) Highlights Key Parameters for ADC Design Journal title: The AAPS Journal Authors: Katie F. Maass, Chethana Kulkarni, Alison M. Betts, K. Dane Wittrup Subject(s): Medicine
Development of a Preclinical PK/PD Model to Assess Antitumor Response of a Sequential Aflibercept and Doxorubicin-Dosing Strategy in Acute Myeloid Leukemia Journal title: The AAPS Journal Authors: Gerald J. Fetterly, Urvi Aras, Deepika Lal, Michael Murphy, Patricia D. Meholick, Eunice S. Wang Subject(s): Medicine
Assessment of the Impact of Dosing Time on the Pharmacokinetics/Pharmacodynamics of Prednisolone Journal title: The AAPS Journal Authors: Jian Xu, Julia Winkler, Sreedharan Nair Sabarinath, Hartmut Derendorf Subject(s): Medicine
Pharmacokinetics/pharmacodynamics and the stages of drug development: Role of modeling and simulation Journal title: The AAPS Journal Authors: Jenny Y. Chien, Stuart Friedrich, Michael A. Heathman, Dinesh P. de Alwis, Vikram Sinha Subject(s): Medicine