A Systematic Analysis of the Sensitivity of Plasma Pharmacokinetics to Detect Differences in the Pulmonary Performance of Inhaled Fluticasone Propionate Products Using a Model-Based Simulation Approach Journal title: The AAPS Journal Authors: Benjamin Weber, Guenther Hochhaus Subject(s): Medicine
Evaluation of Approaches to Deal with Low-Frequency Nuisance Covariates in Population Pharmacokinetic Analyses Journal title: The AAPS Journal Authors: Chakradhar V. Lagishetty, Stephen B. Duffull Subject(s): Medicine
Rapid Sample Size Calculations for a Defined Likelihood Ratio Test-Based Power in Mixed-Effects Models Journal title: The AAPS Journal Authors: Camille Vong, Martin Bergstrand, Joakim Nyberg, Mats O. Karlsson Subject(s): Medicine
Performance of Methods for Handling Missing Categorical Covariate Data in Population Pharmacokinetic Analyses Journal title: The AAPS Journal Authors: Ron J. Keizer, Anthe S. Zandvliet, Jos H. Beijnen, Jan H. M. Schellens, Alwin D. R. Huitema Subject(s): Medicine
Holford NHG and Sheiner LB “Understanding the Dose-Effect Relationship-Clinical Application of Pharmacokinetic-Pharmacodynamic Models”, Clin Pharmacokin 6:429–453 (1981)—The Backstory Journal title: The AAPS Journal Authors: Nick Holford Subject(s): Medicine
Modeling Subpopulations with the $MIXTURE Subroutine in NONMEM: Finding the Individual Probability of Belonging to a Subpopulation for the Use in Model Analysis and Improved Decision Making Journal title: The AAPS Journal Authors: Kristin C. Carlsson, Radojka M. Savi, Andrew C. Hooker, Mats O. Karlsson Subject(s): Medicine
Informatics: The fuel for pharmacometric analysis Journal title: The AAPS Journal Authors: Thaddeus H. Grasela, Jill Fiedler-Kelly, Brenda Cirincione, Darcy Hitchcock, Kathleen Reitz, Susanne... Subject(s): Medicine
Concepts and Challenges in Quantitative Pharmacology and Model-Based Drug Development Journal title: The AAPS Journal Authors: Liping Zhang, Marc Pfister, Bernd Meibohm Subject(s): Medicine
Dashboard Systems: Implementing Pharmacometrics from Bench to Bedside Journal title: The AAPS Journal Authors: Diane R. Mould, Richard N. Upton, Jessica Wojciechowski Subject(s): Medicine
Challenges in the transition to model-based development Journal title: The AAPS Journal Authors: Thaddeus H. Grasela, Jill Fiedler-Kelly, Cynthia A. Walawander, Joel S. Owen, Brenda B. Cirincione,... Subject(s): Medicine