The histopathological effects of salvia officinalis on the kidney and liver of rats

The histopathological effects of salvia officinalis on the kidney and liver of rats


  • Journal title: Scientific Journal of Medical Science
  • ISSN: 2322-5025 (online)
  • Publisher: Sjournals
  • Country of publisher: iran, islamic republic of
  • Platform/Host/Aggregator: Sjournals
  • Date added to EuroPub: 2017/Feb/20

Subject and more

  • LCC Subject Category: Dentistry and Oral Surgery, Nursing, Pathology and Forensics, Pharmacology, Pharmacy, Physiology, Surgery, Toxicology
  • Publisher's keywords: Kidney, Liver, Normal saline, Histopathology, Sprague-Dawley Rats
  • Language of fulltext: english
  • Full-text formats available: PDF
  • Time From Submission to Publication: 3


    D.A. Adekomi*| Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., T.D. Adeniyi| Department of Anatomy, College of Medicine, Osun State University, Osogbo, Osun State, Nigeria., A.M. Afodun| Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria., K.K. Quadri| Department of Physiology, University of Lagos, Lagos, Nigeria.


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The aim of this investigationwas to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old)were randomly assigned into two groups; A and B. Aqueous extract of S.officinalis leaves (300 mg/kg body weight) was administered orally to therats in group B while the rats in group A received equal volume of normalsaline for 14d. At termination of treatment, the histopathology of the kidneyand liver were assessed. The kidney and the liver in the extract treated ratdisplayed organized and preserved histological profile. Our findings suggestthat S. officinalis has no deleterious effects on the kidney and liverof the rats.

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