13 PREVALENCE AND PREDICTORS OF MICROALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A CROSS-SECTIONAL OBSERVATIONAL STUDY
Journal Title: Indian journal of applied basic medical sciences - Year 2015, Vol 17, Issue 24
Abstract
Backgrounds & Objectives: Albuminuria is a well-known predictor of poor renal outcomes in patients with type 2 diabetes and in essential hypertension. Albuminuria has also been shown more recently to be a predictor of cardiovascular outcomes in these populations. This review discusses the measurement of albuminuria and the association between albuminuria and adverse cardiovascular and renal outcomes in type 2 diabetes and hypertension. Methods: 1280 type 2 diabetic patients attending a diabetes centre in civil hospital campus, Ahmadabad were recruited for the study. Urinary albumin concentration was measured by immune turbodimetric assay. Microalbuminuria was diagnosed if the urinary albumin excretion was >30 mg/g of creatinine. Results : Overall prevalence of microalbuminuria was 36.3% (95% confidence interval 33.8 to 38.9). The microalbuminuric patients had significantly increased systolic and diastolic blood pressure compared to normoalbuminuric subjects (p<0.01). The prevalence of microalbuminuria increased with the increase in duration of diabetes. Interpretation & Conclusion: The presence of albuminuria is a powerful predictor of renal and cardiovascular risk in patients with type 2 diabetes and hypertension. Physicians should measure urinary albumin excretion in patients with type 2 diabetes and hypertension routinely and be as aggressive in treating this modifiable risk factor as they do blood pressure, cholesterol, or blood glucose.
Authors and Affiliations
Janardan Bhatt, Dr. Ashok Goswami
Keywords
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