A comparative study of dexmedetomidine and nalbuphine as an adjuvant to bupivacaine in lower limb surgeries done under epidural anaesthesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 3, Issue 1
Abstract
Aims and Objectives: To compare the clinical profile of Nalbuphine and Dexmedetomidine as an adjuvant to Bupivacaine when administered epidurally with respect to sensory and motor blockade, level of sedation and duration of analgesia. Material and Methods: A study was carried out in the Department of Anaesthesiology of Indira Gandhi Government Medical College and Hospital, Nagpur from Nov 2014 to October 2016. The study included 70 adult patients undergoing infraumbilical and lower limb surgeries in epidural anaesthesia. Assessment of motor blockade was done with Modified Bromage Scale. Degree of pain was evaluated by Visual Analogue Scale. Level of Sedation was assessed by Five Point Scale. Result: There was statistically significant difference between the groups for onset of sensory block, duration of analgesia and reversal of motor blockade. The onset of motor blockade, time to achieve maximum sensory and motor blockade, sedation score, Visual analogue scale score were comparable between the groups. Conclusion: Dexmedetomidine is a better adjuvant to Bupivacaine for epidural anaesthesia when compared to Nalbuphine as it provides earlier onset of sensory blockade, prolonged duration of sensory block and postoperative analgesia with stable vitals and minimal side effects.
Authors and Affiliations
Sonali M Khobragade, Jagdish Kalbhor, Ruchi Saran, Sandhya Manjrekar, Soma Cham
Keywords
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