INVITRO ANTI-INFLAMMATORY ACTIVITY OF STRYCHNOS POTATORUM LINN SEED BY HRBC MEMBRANE STABILIZATION
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 3
Abstract
In the present study, strychnos potatorum linn belonging to the family Loganiaceae (Strychnaceae) was studied. It is a folkloric medicinal plant used to treat antibacterial, antifungal, anti diabetic, antioxidant and anti-inflammatory. Since many flavonoids have remarkable anti-inflammatory activity the present work aims at evaluating the anti inflammatory activity of seeds strychnos potatorum linn by HRBC membrane stabilization method. The prevention of hypo tonicity induced HRBC membrane lysis was taken a measure of anti inflammatory activity. The anti-inflammatory activity of hydroalcholic extract was comparable to that of the standard drug Hydrocortisone. The percentage protection for the hydroalcholic extract and hydrocortisone were 100 at µg/ml. the hydroalcholic extract of strychnos potatorum linn seed has significant anti-inflammatory activity (54.95±0.74).
Authors and Affiliations
V. Vijayakumar Dr C. K. Hindumathy
Keywords
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