A-Alkenoyl Ketene S,S- and N,S-Acetals As Starting For Unexpected and Novel Synthesis of N-Heterocycles
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2013, Vol 6, Issue 1
Abstract
A series of N-heterocycles such as diazaspiro-[4.5]decane, pyrazolo[4,3-d][1,2]-diazepine, imidazo[3,2,1ij][1,8]naphthyridine derivatives or pyrazolo[3,4-b]pyridin-4-ol were synthesized using a-alkenoyl-, a,a-dialkenoyl ketene-(S,S)-acetals 2a-d, 3a-c or a-dialkenoyl ketene-(N,S)-acetal 12 as starting materials. The biological activity of some new synthesized compounds have been investigated.
Authors and Affiliations
Ahmed M. M. El-Saghier, Mansour A. Makhlouf, Naglaa F. H. Mahmoud, Wedad A. El-Adawish
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