A Bibliometric research on Medicinal and Aromatic Plants: A Core Journal Study.
Journal Title: Journal of Pharmacy Research - Year 2011, Vol 4, Issue 11
Abstract
The a im of the s tudy i s to eva lua t e ant i s e rotone rgi c a c t ivi ty of e thyl a c e t a t e ext r a c t of Abrus precatorius leaves on a frog fundus strip by using sumatriptan as a standard. This plant also use as a Abortifacient, Anodyne, Aphrodisiac, Antimicrobial, Diuretic, Emetic, Expectorant, Febrifuge, Hemostat, Laxative, Purgative, Refrigerant, Sedative, Vermifuge. Studies of twins indicate a 60 to 65 percent genetic influence upon their propensity to develop migraine headache. Moreover, fluctuating hormone levels indicate a migraine relation: 75 percent of adult patients are women, although migraine affects approximately equal numbers of prepubescent boys and girls; propensity to migraine headache is known to disappear during pregnancy, although in some women migraines may become more frequent during pregnancy. The leaves of Abrus precatorius is on soxhlet extraction with ethyl acetate shown presence of Alkaloids, Carbohydrate, Proteins, Tannins, Saponins and Amino acids and Antiserotonergic activity on frog fundus strip shown (Graded dose response) contraction in a dose of 4.25 mg and 8.25 mg on comparison with sumatriptan as a standard .
Authors and Affiliations
* Ms. S. Lakshmi, ** Dr. A. Ganesan, *** Dr. Daya Sridhar
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