A Case of Rodenticide Poisoning with Acute Fulminant Hepatic Failure: A Case Report
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 9
Abstract
Rodenticides are a heterogeneous group of compounds that exhibit markedly different toxicities to humans and rodents. They are among the most toxic substances regularly found in homes. Predominant rodenticide exposure is anticoagulant rodenticides, zinc phosphide, thallium, barium carbonate and phosphorous. Ratol is a rodenticide available in most of the households and is a common suicidal or accidental poisoning. Ratol contains 3% whitephosphorous (yellow phosphorous). White phosphorous is a general protoplasmic poison causing multiorgan failure at lethal doses. Liver injury is common; however, most victims of phosphorous intoxication die before overt lesions develop. White phosphorous lethal dose for humans is around 60 mg (1mg/kg). When consumed at lethal doses patients present late (>72 hours of ingestion) with multiorgan dysfunction with high mortality rate (100%). We hereby present a 34-year-old female, came with history of alleged history of consumption of around 2g of Ratol paste 2 days prior to presenting to hospital with complains of nausea and abdominal pain. Her vitals were stable having mild scleral icterus and epigastric tenderness. Liver function tests revealed elevated bilirubin levels and deranged coagulation profile. Other parameters were normal. She was given supportive treatment. Her liver enzymes and coagulation profile improved over next 10 days
Authors and Affiliations
Dr Harshitha R
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