A Case of Triple Arthritis: Tuberculosis, MRSA and Gout in One Knee
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 8, Issue 8
Abstract
Aim: To report a case of concurrent tuberculous and bacterial arthritis in chronic tophaceous gout. Presentation of the Case: A 59-year old Filipino male patient consulted for sensorial changes with four-month progressive swelling of the right knee draining non-foul smelling yellowish discharge with chalky material. He eventually had arthrocentesis of right knee. Blood cultures were all negative. Acid fast bacilli were present both in the synovial fluid and endotracheal aspirate. Endotracheal aspirate grew Mycobacterium tuberculosis. Synovial fluid grew methicillin-resistant Staphylococcus aureus (MRSA). He was treated with prednisone, clindamycin, colchicine, febuxostat, tramadol, and anti-tuberculous medications. He failed to undergo surgery. Patient eventually had fatal myocardial infarction. Discussion: To our knowledge, this is the first report of concurrent tuberculous and bacterial (MRSA) arthritis in gout. Conclusion: This case highlights the possible differential diagnoses especially infections among patients with chronic tophaceous gout. Concurrent tuberculosis and bacterial arthritis can complicate the management of these patients. Hence, microbiologic and crystal analysis of synovial fluid is a very important part of the work-up to tailor the early, specific treatment for these patients.
Authors and Affiliations
Joey Tabula, Maricar Josephine Angeles, Agnes Mejia
Low Concentration DMSO Stimulates Cell Growth and In vitro Transformation of Human Multiple Myeloma Cells
Aims: To evaluate the effect of Dimethyl sulfoxide (DMSO) on multiple myeloma (MM) cells. Study Design: Experimental study. Place and Duration of Study: Department of Pathology and Genomic Medicine, the Methodist Hospita...
Impact of a Physical Reconditioning Program on the Quality of Life of Patients Following Coronary Artery Bypass, with or without Led Therapy: Preliminary Results
Aims: Analyse the impact of a physical recondition program (PRP) on Quality of Life (QOL), associated or not to LED therapy on sternotomy after coronary-artery bypass graft (CABG). Study Design: Follow-up after a clinic...
Transabdominal and Transrectal Sonographic Variation of the Prostate Volume and Dimensions: In Evaluation of Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is the non-malignant enlargement of the prostate. Estimation of Prostate volume and dimensions contribute significantly to the management of BPH. Correlations between the trans-abdomina...
A Review of Helicobacter pylori Infection in Patients with Diabetes Mellitus
Gastrointestinal symptoms, such as abdominal discomfort, chronic abdominal pain, dysphagia, heartburn, nausea, vomiting, diarrhea and constipation are more common in patients with Diabetes Mellitus (DM) than in the gener...
Combined Spinal-epidural Anesthesia for Hip Fracture Surgery in Two Geriatric Patients with Low Ejection Fractions
Aims: To present the combined spinal-epidural anesthesia and postoperative analgesia in two geriatric patients, with low Ejection Fractions (EF) that underwent hip fracture surgery. Presentation of Case: Herein, 90 and 1...