A case report of COVID-19-associated acute necrotizing encephalopathy
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 3
Abstract
This article reports one case of adult COVID-19-associated acute necrotizing encephalopathy (ANEC) .The patient developed disturbance of consciousness and seizure on the 12th day after SARS-CoV-2 infection. Imaging showed significant swelling and signal changes in the bilateral thalamus, brainstem, cerebral hemisphere and cerebellar hemisphere, which were consistent with the characteristic images of Acute necrotizing encephalitis (ANE). Although methylprednisolone shock therapy and high-dose human immunoglobulin therapy were given early, the patient died. ANEC often starts quickly and progresses rapidly, unconsciousness and seizure are the main manifestations. Imaging features of thalamic and subtentorial symmetry and multifocal lesions are specific for diagnosis, but the treatment and prognosis still face challenges and need further study.
Authors and Affiliations
Li ZHAO, Xianzhi LI, Liting YAN, Yi LI, Xiaoqi WANG, Xiao. YANG
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