A case report of Parkinson disease complicated with myasthenia gravis
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 7
Abstract
This case report described an 80-year-old male patient with Parkinson disease (PD) complicated with myasthenia gravis (MG). Six years ago,the patient was diagnosed with PD based on the motor symptoms including bradykinesia and static tremor and treated with levodopa-benserazide and piribedil sustained-release tablets. He was admitted to the hospital due to left eyelid ptosis one month ago. The result of Neostigmine test was positive and anti-acetylcholine receptor (AChR) antibodies of serum was positive,which met the diagnostic criteria for myasthenia gravis (MG).The symptom of MG improved significantly after treatment with glucocorticoid and pyridostigmine but the PD symptoms worsened. The symptoms of PD were improved after withdrawal of pyridostigmine and use of the levodopa-benserazide and his condition maintained stable at 3 years of follow-up. The PD complicated with MG was fairly rare. We also reviewed the literature on the possible comorbidity mechanism and treatment strategies to improve the comprehensive understanding and ability of diagnosis and treatment of clinicians.
Authors and Affiliations
Li YANG, Fangming LI, Xiaowu CHEN, Hongya. ZHANG
Keywords
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- EP ID EP750524
- DOI 10.3969/j.issn.1002-0152.2024.07.007
- Views 27
- Downloads 0
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