Progress of long chain non-coding RNAs in the inflammatory response to cerebral ischemia-reperfusion injury
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 5
Abstract
Inflammatory response is one of the key mechanisms of cerebral ischemia/reperfusion injury (CIRI), which seriously affects the prognosis of patients. In recent years, it has been found that long non-coding RNA (LncRNA) is closely related to the inflammatory response of cerebral ischemia/reperfusion injury, and can affect the development and prognosis of CIRI through multiple pathways. The article reviews and summarizes the LncRNAs and their action pathways affecting the inflammatory response in CIRI. The article preliminary explores the possible mechanisms by which LncRNAs affect CIRI, and also briefly summarizes the drugs related to LncRNA therapy. In order to provide new therapeutic targets and research ideas for the treatment of CIRI.
Authors and Affiliations
Lei LI, Xinrui LI, Ying WANG, Chuyan LI, Yuhong. ZHU
Keywords
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- EP ID EP750507
- DOI 10.3969/j.issn.1002-0152.2024.05.010
- Views 13
- Downloads 0
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Progress of long chain non-coding RNAs in the inflammatory response to cerebral ischemia-reperfusion injury
Inflammatory response is one of the key mechanisms of cerebral ischemia/reperfusion injury (CIRI), which seriously affects the prognosis of patients. In recent years, it has been found that long non-coding RNA (LncRNA) i...