A Charge Transfer Determination of Paracetamol with Picric Acid
Journal Title: Archives of Pharmacy & Pharmacology Research - Year 2018, Vol 1, Issue 2
Abstract
A cost effective and sensitive spectrophotometric method has been developed for the assay of paracetamol in pure and commercial forms. The method employed was charge transfer complexation. Paracetamol formed a 1:2 stoichiometric ratio with picric acid. The complex was quantified at 500nm. Beer –Lambert’s law was obeyed within a concentration range of 5-10μg/ml with molar absorptivity of 2.6 x104Lmol-1cm-1. The method was used for the determination paracetamol in pure and commercial forms with percentage mean recovery of 95%.
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- EP ID EP593826
- DOI 10.33552/APPR.2018.01.000507
- Views 76
- Downloads 0
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