A clinical correlation of conjunctival microangiopathy with grades of retinopathy in type 2 diabetes mellitus

Journal Title: Medical Journal Armed Forces - Year 2017, Vol 73, Issue 3

Abstract

Background: Conjunctival microangiopathy has been described among diabetics similar to retinal vessel angiopathy. Correlation of these conjunctival microangiopathy changes with retinopathy may form the basis of screening by external examination without expert fundus evaluation. Methods: Conjunctival vessels widths and tortuous segment length of conjunctival vessels of 96 patients with type 2 diabetes mellitus were photographed and measured by the Zeiss Fundus camera Visupac software. The measurements were correlated with retinopathy grade in those eyes. Results: The mean conjunctival vessel width was 40.61 m (SD 17.25) with a uniform increase from 34.4 m (SD 8.70) in mild NPDR to 53.50 m (SD 33.45) in the PDR group which was statistically significant ( p < 0.01). The tortuous conjunctival vessel segment length increased from 711.51 m (SD 83.90) in the mild NPDR group to 921.94 m (SD 129.26) in those with PDR ( p < 0.01). Vessel width greater than 80 m was seen only in PDR and tortuosity values greater than 900 m were seen in severe grades (severe NPDR and PDR). Both conjunctival vessel width and tortuosity showed a positive statistical correlation with increasing severity of retinopathy (r = 0.386, r2 = 0.149 and r = 0.645, r2 = 0.415). Conclusion: A positive correlation was seen between conjunctival vessel width and tortuosity with severity of retinopathy. Widths over 80 m and tortuous segment length over 900 m are suggestive of severe grades of retinopathy.

Authors and Affiliations

M A Khan

Keywords

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  • EP ID EP618203
  • DOI 10.1016/j.mjafi.2017.01.005
  • Views 58
  • Downloads 0

How To Cite

M A Khan (2017). A clinical correlation of conjunctival microangiopathy with grades of retinopathy in type 2 diabetes mellitus. Medical Journal Armed Forces, 73(3), 261-266. https://europub.co.uk/articles/-A-618203