A CLINICAL STUDY AND SURGICAL MANAGEMENT OF CARCINOMA OESOPHAGUS AT KIMS, HUBLI
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 60
Abstract
BACKGROUND Carcinoma oesophagus is aggressive tumour with poor prognosis occurring in mid to late adulthood with most cases presenting in the late stages. Surgical therapy remains the main stay therapy. Survival rate varies from 10 to 45% depending upon the stage. Primary goal of palliation is restoration of swallowing, relief of pain and local control of disease. The aim of the study is to study the- 1. Various clinical modes of presentation of oesophageal cancer and their correlates. 2. Outcome of the transhiatal oesophagectomy surgery. 3. Histopathological profile of the tumour. MATERIALS AND METHODS 30 patients with oesophageal carcinoma (of lower one third) admitted at KIMS, Hubli, were enrolled. Data was collected using a pretested proforma. The cases were subjected to surgery (transhiatal oesophagectomy) after relevant investigations and confirmation of diagnosis by endoscopic biopsy. RESULTS Males are more commonly affected. Maximum incidence of disease was noted in 5th and 6th decades of life. 33.3% cases were tobacco chewers and 20% consumed alcohol. Dysphagia was the commonest presenting feature seen in all the 30 patients. Weight loss was present in 24 patients. Morphologically, 53.3% had ulcerative growth and 46.6% had ulceroproliferative growth of lesion. Most common postoperative complications was pneumonia and anastomotic leak. Postoperative mortality rate was 20%. Most common histological variety of carcinoma oesophagus was squamous cell carcinoma. CONCLUSION Smoking, tobacco chewing and alcohol consumption are important risk factors in development of carcinoma oesophagus. Larger study and regular follow up are required for long-term survival rate estimation.
Authors and Affiliations
Balachandra Parashuram Sanganal, Shivanagouda Yallappagouda Mulkipatil
DIAGNOSTIC ACCURACY OF ANTI-THYROID ANTIBODIES IN HASHIMOTO’S THYROIDITIS
BACKGROUND Hashimoto’s thyroiditis is the most common cause of hypothyroidism in Iodine sufficient areas. Diagnosis depends on histopathological or cytological features. The accuracy of autoantibodies among hypothyroid p...
A CLINICAL STUDY OF MATERNAL DEATHS DUE TO PPH
OBJECTIVES: A study of maternal death conducted to evaluate various factors responsible for maternal deaths. To identify complications in pregnancy, a childbirth which result in maternal death, and to identify opportunit...
FREQUENCY AND PATTERN OF HEADACHE IN MEDICAL RESIDENTS AND NON-MEDICAL STUDENTS IN A TERTIARY CARE TEACHING HOSPITAL IN NORTH INDIA
BACKGROUND Headache is quite prevalent in general population. Few studies have been done on medical residents and comparison between headache prevalence and types in medical and non-medical student groups is quite lackin...
YELLOW PHOSPHOROUS POISONING: AN OBSERVATIONAL STUDY FROM A TERTIARY CARE HOSPITAL
BACKGROUND Yellow phosphorous, a rodenticide, is a lethal toxin in humans that can cause damages to hepatic, cardiovascular, gastrointestinal and the renal systems and it carries significant morbidity and mortality. The...
A STUDY OF MATERNAL MORTALITY AT A TERTIARY REFERRAL CENTRE
To study the various causative factors of maternal mortality and to chalk out recommendations to reduce the same. METHODS: A retrospective confidential review of maternal deaths was done from the hospital case records, d...