A CLINICAL STUDY OF SERUM ELECTROLYTES (NA, K, CL) AND SERUM MAGNESIUM LEVELS IN PATIENTS OF ACUTE MYOCARDIAL INFARCTION
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 61
Abstract
BACKGROUND Myocardial Infarction (MI) is the term used to describe a state of myocardial necrosis secondary to an acute interruption of the coronary blood supply.1 It is one of the manifestations of coronary heart disease leading to morbidity and mortality.2 World Health Organization (WHO) has declared cardiovascular disease as a modern epidemic.3 Most of the myocardial infarctions results due to disruption in the vascular endothelium associated with atherosclerotic plaque, which in turn stimulates the formation of an intracoronary thrombus, which further leads to occlusion of coronary artery blood flow, if this occlusion persists for more than 20 minutes can results in irreversible myocardial cell damage and even cell death. Severity of the condition is dependent on three factors- the level of occlusion, length of time of occlusion and presence or absence of collateral circulation. Rupturing of the plaque causes complete coronary occlusion, which usually results in STEMI. This arises most often from a plaque that previously caused less than 50% lumen occlusion.4 Clinical diagnosis as well as diagnostic classification is commonly based on electrocardiographic findings to differentiate between the two types of MI. There are mainly two types, STEMI and NSTEMI. Complications of acute MI are many, which in turn leads to high incidences of mortality, but among all arrhythmias, cardiogenic shock and heart failure are found to be commonly associated with it along with electrolyte disturbances. The aim of the study is to observe the prevalence of various electrolyte (Na, K, CL and Mg) imbalances along with complication of cardiogenic shock, arrhythmias and heart failure in the patients of acute myocardial infarction. MATERIALS AND METHODS This is a prospective study in which the 100 patient admitted with signs and symptoms of acute myocardial infarction diagnosed clinically both males and females were selected over 1 year. Patients presented with symptoms of AMI within 48 hours of onset with history of chest discomfort, ECG changes of acute myocardial infarction and rise of cardiac enzymes. RESULTS In this study, mean age of male patients 54.04 ± 11.49 and female patients 60.30 ± 11.78. The serum magnesium, sodium and potassium levels were significantly lower in the AMI patients at baseline and gradually becomes near normal on 4th day. CONCLUSION So, estimation of serum magnesium, sodium and potassium levels can help to assess prognosis in AMI patients.
Authors and Affiliations
Ketan Bharatbhai Parmar, Raj N Sharma, Jyotin Shah
Keywords
Related Articles
- EP ID EP228258
- DOI 10.18410/jebmh/2017/736
- Views 79
- Downloads 0
COMPARISON OF SAFETY AND EFFICACY OF LEVOSULPIRIDE AND ITOPRIDE IN TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE
BACKGROUND Gastroesophageal Reflux Disease (GERD) is a common condition caused by reflux of the liquid acidic contents of the stomach into the oesophagus. Prokinetic medications can be used to treat or control the diseas...
LEIOMYOMAS IN HYSTERECTOMY SPECIMENS: A CLINICOHISTOPATHOLOGICAL STUDY
BACKGROUND Uterine leiomyomas are the most common uterine neoplasms. They occur in as many as 75% of uteri. All women of reproductive age group are vulnerable and may experience clinical features like pain, abnormal uter...
MANAGEMENT OF PSEUDOARTHROSIS OF SHAFT HUMERUS BY PLATING (FIVE YEARS FOLLOW UP) – A CASE STUDY
Pseudoarthrosis is a condition where union at fracture site is very difficult to obtain. But sticking to the very basic principles of management of non-union – that is freshening at fracture site, removal of sclerotic bo...
COMPARATIVE STUDY OF DIFFERENTIAL EXPRESSION OF CYCLIN-E IN NORMAL PLACENTA, HYDROPIC ABORTUS AND GESTATIONAL TROPHOBLASTIC DISEASE
BACKGROUND Gestational Trophoblastic Disease (GTD) encompasses a heterogeneous group of lesions, characterised by proliferation of pregnancy associated trophoblastic tissue. According to WHO, GTD was classified into thre...
RETAINED PLACENTA AND ITS CLINICAL MANAGEMENT
102 cases of retained placenta admitted to Cheluvamba Hospital, Department of Obstetrics and Gynecology, Mysore Medical College between 1st January 1995 to 5th February 1997 were studied with a name to identify high risk...