A clinico - pathological correlation of patients with dengue hemorrhagic fever at tertiary health care center

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A clinico - pathological correlation of patients with dengue hemorrhagic fever at tertiary health care center

Journal Title: Medpulse International Journal of Pediatrics - Year 2017, Vol 3, Issue 1

Abstract

Background: Dengue fever is an infectious disease which is difficult to distinguish from other viruses as there are no specific markers that can diagnose the disease early. Aims and Objectives: To Study Clinico- Pathological correlation of patients with Dengue Hemorrhagic fever at tertiary health care center. Methodology: It was a hospital based prospective study done over a period of one year from 1st July 2002 to 30th June 2003 in the Department of pediatrics, wanless hospital and Government medical college, Miraj. Fifty children admitted to pediatric intensive care unit during the above period with clinical diagnosis of DHF/DSS were included in the present study. Children of 1 month to 16 years of age, fulfilling WHO criteria for the diagnosis of DHF/DSS were included. Result: In our study, we have found that Out of 50 patients, 35 (70%) aged 6 to 12 years, 9 (18%) patients aged 13 to 16 years while 6 (12%) aged less than 5 years, youngest being 7 month old infant. Of total 50 patients, 15 (30%) patients had grade I and 17 (34%) had grade II severity. While 12 (24%) patients had grade III and 6 (12%) had grade IV severity. Tourniquet test was positive in 15 (100%) patients with Grade-I, and 9 (52.9%) patients with Grade II severity. Only 4 (33.3%) patients with grade III and I (16.7%) patients with Grade IV severity had positive tourniquet test. In 7 (14%) patients it was less than 4,000 (leucopenia) while 12 (24%) patients had count more than 11,000. (Leukocytosis). All fifty patients had thrombocytopenia (<1,00,000/mm3) of which 26 (52%) had moderate thrombocytopenia while 16 (32%) patients had severe and 8 (16%) had mild thrombocytopenia. Rise in Hct. Concentration by >20% was observed in 31 (73.8%) of the 42 patients in whom it could be computed. Elevated liver enzymes were found in a total of 34 (68%) patients of which 24 (70.6%) had predominantly SGOT rise while 10 (29.4%) had predominantly SGPT rise. Thirty-one (62%) of the 50 patients were found to have hypoproteinemia. Conclusion: It can be concluded from our study that the most common, age group in our study found to be 6 to 12 years; WHO grade I and Tourniquet test was most common in Grade I , Most of the patients showed Thrombocytopenia, Raised Hematocrit seen in 20 % persons also some patients showed Elevated liver enzymes.

Authors and Affiliations

Bhavesh B Shah, Sara Dhanawade

Keywords

Dengue Hemorrhagic DHF/DSS WHO Grades of DHF

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EP ID EP260306
DOI -
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