A comparative Clinical Study of Intrathecal Hyperbaric Bupivacaine 0.5% with 25 mg Pethidine Versus 25 mg Tramadol for Infraumbilical Surgeries
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 9
Abstract
Introduction: Requirement of post operative pain relief is mandated due to therapeutic reasons. It was this need of a cost effective but efficient mode of additional post operative analgesia which prompted us to study and compare the quality of analgesia and complications of intrathecal administration of Pethedine and Tramadol along with intrathecal hyperbaric Bupivacaine. Design: This was a prospective, randomised, double-blind study. Material and methods: 60 patients of American Society of Anesthesiologists Grade I and II randomized into two groups using Envelope method. Group A:- Subarachnoid block given with [3ml 0.5% Bupivacaine heavy + 25 mg Pethedine]. Group B:- Subarachnoid block given with [3ml 0.5% Bupivacaine heavy + 25mg Tramadol]. Outcome measures: Patients were observed for any haemodynamic changes, side effects and complications viz Hypotension, Bradycardia, Pruritis, Sedation, Nausea, Vomiting, Shivering and any other side effects and managed accordingly upto a period of 8 hours post-operatively and for post operative analgesia. Results: Mean duration of postoperative analgesia in the Pethedine and the Tramadol groups was 316.10±8.27min and 405.60±10.25min respectively (P <0.001). Haemodynamic changes along with incidence and severity of side effects for both Pethidine and Tramadol are similar when used intrathecally as adjuvant to Bupivacaine. Conclusion: From our study we conclude that both Pethidine and Tramadol can be used intrathecally along with hyperbaric Bupivacaine to effectively prolong duration of post operative analgesia but prolongation is more with Tramadol than with Pethidine. There are similar side effects in both the groups which can be easily controlled with medications
Authors and Affiliations
Ruchi Tandon, Chandrakant Waikar, S. N Agrawal
Keywords
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