A comparative double blinded study of levobupivacaine and ropivacaine in USG guided supraclavicular brachial plexus block
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Existing local anaesthetics are known for its wide and unpredictable latency of nerve block, as well as its propensity for neuro and cardiotoxicity. Ropivacaine has a potential clinical advantage during neural blockade. Bupivacaine possessed the same anaesthetic activity but had less cardiac and neural toxic effects than bupivacaine. The purpose of this clinical study was to compare the onset, duration and quality of sensory and motor blockade and postoperative analgesia between groups of patients receiving supraclavicular brachial plexus block with 0.5% ropivacaine and 0.5% levobupivacaine under USG guidance. Material and Methods: The study was conducted in two groups of 30 patients each. The patients were randomly allocated in two groups by sealed envelope technique as – Group R (received 30 ml of 0.5% Ropivacaine) and Group L (received 30 ml of 0.5%Levobupivacaine).The onset of sensory and motor block, their duration, and duration of postoperative analgesia were recorded and compared for both groups. Results: The mean onset time and mean peak time for sensory and motor block was significantly faster in Group R as compared to Group L.The mean duration of sensory and motor block was 8.13 hours and 10.05 hrs in group R as compared to 10.06 hours and 11.79 hrs in group L respectively.The mean duration of postoperative analgesia was significantly higher in group L (13.20±1.61) hours as compared to (9.50±1.43) hours in group R. Conclusion: The onset of action of sensory, motor was early in ropivacaine group with faster recovery of motor function as compared to equivalent dose of levobupivacaine. Ropivacaine offers an advantage where early recovery of motor function is desired in postoperative period. Levobupivacaine has a better profile in terms of duration of analgesia and should be considered when postoperative analgesia is a concern but not when early return of motor activity is required.
Authors and Affiliations
Anuja A Rathore, Jyotsna P Bhosale
Keywords
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