A Comparative Histochemical Study of Mucins Produced by Brunner’s Glands of Guinea Pig, Rabbit and Goat

Abstract

Mucins are high-molecular weight glycoproteins that have gel-forming properties which are highly glycosylated and which in turn are responsible for their protective function. Normal distribution of mucin and its alteration in various inflammatory, benign and malignant lesions of gastrointestinal tract has aroused interest in the field of histochemistry. Brunner’s glands, located in the submucosa of the proximal duodenum ,in general produce a mucous secretion and exist in all mammalian species. For the present study, tissues were taken from the proximal part of duodenum of guinea pig, rabbit and goat then subjected to various histochemical stains like AB at both pH 1 and 2.5, PAS, Diastase digestion, PAS- Phenyl hydrazine and AB pH 2.5- PAS. It was found that the Brunner’s glands of guinea pig secreted mixture of acid and neutral mucins.In rabbit mucous acini secreted moderate amount of acid mucin and serous acini secreted scanty amount of neutral mucin.Whereas in goat the brunner’s glands secreted negligible amount of acid mucin but substantial amount of neutral mucin.It may be concluded that guinea pig, rabbit and goat were herbivore and had similar eating habits yet their brunner’s glands secreted mucins differently.Hence dietary habits seemed to have no impact on the type of mucins secreted by the brunner’s glands.

Authors and Affiliations

Alka Rashmi Nag, Renu Prasad

Keywords

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  • EP ID EP31030
  • DOI -
  • Views 318
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How To Cite

Alka Rashmi Nag, Renu Prasad (2016). A Comparative Histochemical Study of Mucins Produced by Brunner’s Glands of Guinea Pig, Rabbit and Goat. International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS), 3(3), -. https://europub.co.uk/articles/-A-31030