A COMPARATIVE STUDY OF BLOOD GLUCOSE WITH OR WITHOUT SODIUM FLUORIDE
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 5
Abstract
INTRODUCTION: Glycolysis decreases serum glucose by approximately 5-7% in 1 hour (5-10 mg/dl) in normal uncentrifuged coagulated blood at room temperature. Glycolysis has been found to be inhibited and glucose stabilized at room temperature by adding Sodium Fluoride. Fluoride ions prevent glycolysis by inhibiting enolase. AIM: To determine whether using Sodium fluoride as an anticoagulant really has a stabilizing effect on glucose concentration in blood even after 4 hours of collection. METHOD: Prospective study of 100 patients. Samples collected with or without sodium fluoride and glucose estimation done after 4 hours of collection. RESULTS: Glucose level difference between sterile vial sample and fluoride vial sample after 4 hour of storage at room temperature was statistically significant. CONCLUSION: Fluoride has a very strong stabilizing effect on serum glucose concentration.atleast upto 4 hours storage at room temperature
Authors and Affiliations
Dr. Arpita Saxena, Dr. Monigopa Das
Keywords
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