A Comparative Study of Cardiac Autonomic Function Indices among Young and Old Healthy Individuals of Western Rajasthan by CanWin
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 6
Abstract
Abstract: Ageing in humans is characterized by alterations in the integrative regulation by the cardiovascular and autonomic nervous system (ANS) systems. Proper function of the ANS is achieved through a balance of parasympathetic and sympathetic out flow from the brain and this balance is shifted with advancing age towards decreased parasympathetic function and increased sympathetic discharge to the heart, vasculature and other organs. To observe the influence of aging process on autonomic nerve functions the non- invasive autonomic function tests were carried out by CAN Win Analysis System in 125 healthy subjects between the age group of 20 to 70 years and divided into five groups, each comprises of 25 subjects. The Parasympathetic activity was assessed by heart rate response to deep breathing (DB),30:15 ratio and valsalva maneuver(VM) and with age results of parasympathetic tests, revealed a significant linear decline in value .Assessment of sympathetic activity by blood pressure response to standing test revealed that there is linear increase in Systolic blood pressure (SBP) and blood pressure response to sustained handgrip exercise revealed a significant decline in Diastolic Blood Pressure (DBP) with age.No gender variation in both sympathetic and parasympathetic function test was observed. From this study it may concluded that ageing process substantially impaired cardiovascular autonomic nerve functions.Autonomic status will have an important bearing on determining the therapeutic strategy and drug action in the elderly in whom there may be altered responsiveness to autonomic reflexes and receptor sensitivity.
Authors and Affiliations
Dr. Kirti Goyal, Dr. Prahlad Kalwan
Keywords
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