A Comparative Study of Dosage of MGSO4in Indian Women with Eclampsia.
Journal Title: Gujarat Medical Journal - Year 2018, Vol 73, Issue 1
Abstract
ObjectiveTo assess the safety and efficacy of a low dose magnesium sulfate regimen for the management of eclampsia in Indian women.Aims & Objectives: 1)To identify the cases of eclampsia who come to dept. Of obstetrics &gynaecology of C.U.Shah medical college, surendranagar. 2)To treat some cases with Pritchard regimen & study the efficacy & safety profile. 3)To treat some cases with Low-dose regimen & study the efficacy & safety profile. 4)To compare the efficacy & safety profile of the two regimens.Methods:Aloading dose consisting of 4 gram of magnesium sulfate intravenously plus 6 gram intramuscularly (3 gram in each buttock) was followed by 4 gram intramuscularly every 4 hours, for 24 hours beyond the last seizure. This regimen was evaluated prospectively with 50 women with eclampsia and the results were compared with Pritchard regimen which was used in 50 women with eclampsia.Results: Conclusion:The low dose regimen was associated with a lower seizure recurrence and a slightly lower maternal mortality. This studyconfirm that Low-dose regime is as effective and safer than Prichard regime.
Authors and Affiliations
Bhavesh Airao, Nishant H. Patel, Bipin Shah
Keywords
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