A COMPARATIVE STUDY OF EFFECT OF P. FALCIPARUM AND P. VIVAX MALARIA ON PLATELET COUNT
Journal Title: International Journal of Basic and Applied Physiology - Year 2014, Vol 3, Issue 1
Abstract
Background & objectives: Malaria is a big menace in India affecting almost 24 million peoples and causing 2.4 deaths per 1, 00,000 populations annually. Malaria affects almost all the organs of body but varieties of typical hematological alterations have been reported. Present study aims to evaluate impact of malaria on platelet count and species specific changes if any. Methods: This study was carried out in Deendayal Upadhyay Govt. Medical College and Hospital, Rajkot 100 known hospitalized cases of malaria. All the hematological parameters including platelet count were tested by SYSMAX KX21 auto analyzer and statistically analyzed among different species. Results: Out of 100 patients, 37 were P. falciparum and 63 were P. vivax cases. 91 cases had thrombocytopenia. 97.29% (36 out of 37) cases with P. falciparum and 87.30% (55 out of 63) cases with P. vivax had thrombocytopenia amongst them 29.73% (11 out of 37) of P. falciparum and 6.35% (4 out of 63) cases with P. vivax had severe low platelet count. The mean values of platelet count are lower than normal in both the infections and statistically significant difference (P value - 0.0071) is seen between P. falciparum and P. vivax. Conclusion: Thrombocytopenia is the leading hematological alterations seen in malaria with statistically significant difference in severity being more deteriorating in P. falciparum cases than P. vivax cases.
Authors and Affiliations
Payal Jivani, Bijal Panchal, Sudha Parmar, Neeta Mehta, Chirag Savaliya, Ashvin Sorani
Keywords
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