A Comparative Study of Intrathecal Bupivacaine with Nalbuphine and Bupivacaine with Fentanyl for Intra and Post-Operative Analgesia in Gynaecological Surgeries
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 11
Abstract
Abstract: Spinal anaesthesia is still the most commonly used technique for gynaecological surgeries as it is economical and easy to administer. Its main drawback is the short duration of action due to these different adjuncts have been used. The reason for mixing opioids and local anaesthetics is that this combination eliminates the pain by acting at two different locations, local anaesthetics acting at the nerve axon and the opioids at the receptor site in the spinal cord. A total 60 patients of ASA grade I and II in the age group of 40-60 years were randomly allocated with their consent in one of the two groupsGROUP A: [ n =30 ] received 0.5% hyperbaric Bupivacaine 15 mg with Nalbuphine 0.8 mgGROUP B: [n =30] received 0.5% hyperbaric Bupivacaine 15 mg with Fentanyl 25 mcg.The characteristics of onset of sensory and motor blockade, intraoperative hemodynamics, respiratory parameters and VAS score and side effects were recorded, tabulated and statistically analyzed. The onset of sensory block was more rapid with Fentanyl than Nalbuphine and this was statistically significant but the duration of post-operative analgesia( sensory and motor) and the effective analgesic time were more prolonged in Nalbuphine group than in Fentanyl group with no statistically significant difference. There was no significant difference found in various hemodynamic, vital parameters intra operatively or any side effects between the two groups.Addition of Nalbuphine to intrathecal Bupivacaine improved the quality of intraoperative and postoperative analgesia with minimal side effects. Keywords:Bupivacaine, Fentanyl, Gynaecological surgeries, Intrathecal, Nalbuphine.
Authors and Affiliations
. Avinash Bapurao Pawar, Thorat PS, Rawat HS
Keywords
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