A Comparative Study of Intrathecal Bupivacaine with Nalbuphine and Bupivacaine with Fentanyl for Intra and Post-Operative Analgesia in Gynaecological Surgeries
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 11
Abstract
Abstract: Spinal anaesthesia is still the most commonly used technique for gynaecological surgeries as it is economical and easy to administer. Its main drawback is the short duration of action due to these different adjuncts have been used. The reason for mixing opioids and local anaesthetics is that this combination eliminates the pain by acting at two different locations, local anaesthetics acting at the nerve axon and the opioids at the receptor site in the spinal cord. A total 60 patients of ASA grade I and II in the age group of 40-60 years were randomly allocated with their consent in one of the two groupsGROUP A: [ n =30 ] received 0.5% hyperbaric Bupivacaine 15 mg with Nalbuphine 0.8 mgGROUP B: [n =30] received 0.5% hyperbaric Bupivacaine 15 mg with Fentanyl 25 mcg.The characteristics of onset of sensory and motor blockade, intraoperative hemodynamics, respiratory parameters and VAS score and side effects were recorded, tabulated and statistically analyzed. The onset of sensory block was more rapid with Fentanyl than Nalbuphine and this was statistically significant but the duration of post-operative analgesia( sensory and motor) and the effective analgesic time were more prolonged in Nalbuphine group than in Fentanyl group with no statistically significant difference. There was no significant difference found in various hemodynamic, vital parameters intra operatively or any side effects between the two groups.Addition of Nalbuphine to intrathecal Bupivacaine improved the quality of intraoperative and postoperative analgesia with minimal side effects. Keywords:Bupivacaine, Fentanyl, Gynaecological surgeries, Intrathecal, Nalbuphine.
Authors and Affiliations
. Avinash Bapurao Pawar, Thorat PS, Rawat HS
Keywords
Related Articles
- EP ID EP372299
- DOI -
- Views 52
- Downloads 0
Safety and Efficacy of High Dose Intravenous Iron Sucrose for Treating Anaemia in Pregnancy
Iron deficiency anaemia is the most common deficiency in women of child bearing age throughout the world and is even more common in pregnancy, as it might be expected from the increasing iron requirement. Approximately 9...
A Study to Evaluate the Effect of Dexmedetomidine as Intrathecal Adjuvant to Ropivacaine for Hemodynamic Stability and Postoperative Analgesia in Gynecological Surgeries
Abstract: Many adjuvants have been used with local anesthetics in spinal anesthesia but none has been found ideal. We have conducted this prospective randomized double blind study to evaluate the effect of intrathecal de...
Demographical Evaluation of Type 2 Diabetes Mellitus and Effect of Prescribed Anti Diabetic Drugs on Maintaining Optimal Glycemic Levels in Diabetic Patients: An Observational Study
Abstract: The aim of the study was to evaluate Type 2 Diabetes Mellitus patients demographically and Effect of Prescribed Anti Diabetic Drugs in maintaining optimal glycemic levels in diabetic patients attending Medicine...
Computerized Tomography Imaging Value in Diagnosing Head Injuries, Compared with Conventional Skull X-rays
Head injuries are the main causes of death in Sudan. The emergency neurosurgery department of Teaching Khartoum Hospital , is the only specialized department in Sudan , which deals with the management of head injury pat...
Imaging of A Rare Prostatic Malignancy Prostatic Sarcoma
Abstract: Prostate malignancy is the second most common cancer in men .But among prostatic malignancies; prostatic stromal sarcoma (PSS) is quite rare accounting for only~ 0.1-0.2% of all malignant prostate tumors. Here...