A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl in Lower Abdominal Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 10
Abstract
Context: Fentanyl was commonly used previously but due to its short duration of analgesia and more requirements of analgesics, efficacy of dexmedetomidine was evaluated by some studies and found to be effective. Aim: To compare the efficacy between dexmedetomidine and fentanyl when used for patients undergoing lower abdominal surgeries Settings and design: Present study was hospital based comparative study carried out at Department of Anesthesiology, Malla Reddy Institute of Medical Sciences. Methods: 60 consecutive eligible patients undergoing surgeries for lower abdomen were divided into two groups of 30 each. First group received dexmedetomidine 5 mcg and the other group received fentanyl 25 mcg. They were compared for the time taken for sensory regression and requirement of analgesics Statistical analysis: Student’s t test was used for mean values and chi square test for proportions. Results: Both the groups were comparable to each other in terms of baseline characteristics, types of surgeries performed. Mean duration of surgery was significantly more in the dexmedetomidine group than fentanyl group. The height of sensory level was significantly different between the two groups. Both the drugs took equal time of three minutes from injection to reach the highest sensory level. But the time required for sensory regression to S1 from highest sensory level was significantly higher for dexmedetomidine group patients compared to fentanyl group patients. The requirement of analgesics was significantly higher for fentanyl group compared to the dexmedetomidine group. Conclusion: Dexmedetomidine was found to be more effective than fentanyl in terms of long lasting anesthesia, and lesser requirement of analgesics.
Authors and Affiliations
Varaprasada Rao T.
Keywords
Related Articles
- EP ID EP548625
- DOI 10.21088/ijaa.2349.8471.51018.22
- Views 87
- Downloads 0
Evaluation of Low Dose Dexmeditomedine as an Adjuvant to Bupivacaine 0.25% in Supraclavicular Brachial Plexus Blocks
Context: The assessment of the efficacy of low dose (30 micrograms) of dexmeditomedine added to 0.25% bupivacaine was studied for the prolongation of the duration of sensory and motor block in supraclavicular brachial pl...
Comparison of Dexmedetomidine with Esmolol as Hypotensive Agents in Elective ENT Surgeries in General Anaesthesia: A Randomized Controlled Trial
Objective: To compare the efficacy of dexmedetomidine as a hypotensive agent with esmolol in elective ENT Surgeries in ASA grade III patients. Methods: This study was a prospective, randomized, double blinded study that...
Selective Left Endobronchial Intubation in Paediatric Cases: Lesson Learnt Using Single Lumen Tube
Background: Selective left endobronchial intubation in right thoracoscopy is technically demanding. We are presenting our mid term experience of selective left bronchus intubation using the previously published maneuver...
A Retrospective Study of Serial Inspection of ACLS Ambulances in a Tertiary Care Facility
Aim: To maximize availability of Ambulance equipment before dispatch. Design: Retrospective observational study. Material and Methods: A team of doctors, nurses and paramedics of our tertiary care central government hosp...
Comparative Study between Intravenous Clonidine and Intravenous Fentanyl to Attenuate Hemodynamic Response to Laryngoscopy and Tracheal Intubation
Background: Laryngoscopy and intubation are associated with acute hemodynamic responses. In susceptible patients even this short period (2-7 minutes) of hypertension and tachycardia can result in myocardial ischemia or i...