A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl in Lower Abdominal Surgeries

Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 10

Abstract

Context: Fentanyl was commonly used previously but due to its short duration of analgesia and more requirements of analgesics, efficacy of dexmedetomidine was evaluated by some studies and found to be effective. Aim: To compare the efficacy between dexmedetomidine and fentanyl when used for patients undergoing lower abdominal surgeries Settings and design: Present study was hospital based comparative study carried out at Department of Anesthesiology, Malla Reddy Institute of Medical Sciences. Methods: 60 consecutive eligible patients undergoing surgeries for lower abdomen were divided into two groups of 30 each. First group received dexmedetomidine 5 mcg and the other group received fentanyl 25 mcg. They were compared for the time taken for sensory regression and requirement of analgesics Statistical analysis: Student’s t test was used for mean values and chi square test for proportions. Results: Both the groups were comparable to each other in terms of baseline characteristics, types of surgeries performed. Mean duration of surgery was significantly more in the dexmedetomidine group than fentanyl group. The height of sensory level was significantly different between the two groups. Both the drugs took equal time of three minutes from injection to reach the highest sensory level. But the time required for sensory regression to S1 from highest sensory level was significantly higher for dexmedetomidine group patients compared to fentanyl group patients. The requirement of analgesics was significantly higher for fentanyl group compared to the dexmedetomidine group. Conclusion: Dexmedetomidine was found to be more effective than fentanyl in terms of long lasting anesthesia, and lesser requirement of analgesics.

Authors and Affiliations

Varaprasada Rao T.

Keywords

Related Articles

Efficacy of Spinal Anaesthesia as a Safer Technique in Laparoscopic Cholecystectomy with Better Outcome

Spinal anaesthesia is always a safe, cost effective and a better option in patients where general anaesthesia can be complicated and to fulfill the purpose of post­operative analgesia. After conducting many upper abdomin...

Single Injection versus Double Injection Ultrasound Guided Supraclavicular Brachial Plexus Block: A Randomised Comparative Study

Ultrasound guided (USG) supraclavicular brachial plexus (SPB) block can be performed either by a single injection (SI) technique, injecting the entire volume of drug in the corner pocket or by a double injection (DI) tec...

Comparison of Dexmedetomidine and Fentanyl as Adjuvants to Ropivacaine in Epidural Anaesthesia for infraumbilical Surgeries: An Observational Study

Aims: To assess the efficacy and compare the duration of analgesia, level of sedation and side effects of 0.75% ropivacaine with 50 mcg dexmedetomidine to 0.75% ropivacaine with 50 mcg fentanyl given epidurally. Study s...

Comparison of Premixed Versus Sequential Administration of Fentanyl as an Adjuvant to Intrathecal Hyperbaric Bupivacaine in Infra-Umbilical Surgeries: A Randomized Controlled Study

Opioids and local anaesthetics administered together intra-thecally have potent synergistic analgesia. Aims and Objectives: To compare the efficacy of premixed versus sequential administration of fentanyl as an adjuvant...

Effects of Lower Doses of Dexmedetomidine on Controlled Hypotension During Middle Ear Surgery

Context: Controlled hypotension is required for middle ear surgery to achieve a bloodless operative field which is achieved by dexmedetomidine. Aims: To study and assess the efficacy of dexmedetomidine infusion in lower...

Download PDF file
  • EP ID EP548625
  • DOI 10.21088/ijaa.2349.8471.51018.22
  • Views 79
  • Downloads 0

How To Cite

Varaprasada Rao T. (2018). A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl in Lower Abdominal Surgeries. Indian Journal of Anesthesia and Analgesia, 5(10), 1728-1733. https://europub.co.uk/articles/-A-548625