A Comparative Study of Intubating Conditions and Cardiovascular Effects of Rocuronium and Succinylcholine in Rapid Sequence Induction and Intubation
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
Aim of Study: Succinylcholine is the most frequently used muscle relaxant for rapid sequence intubation but sometimes the need arises to use another agent. The aim of our study is to compare the haemodynamic profile and intubating conditions of rocuronium with that of succinylcholine during rapid sequence induction and intubation. Material and Methods: 80 patients posted for emergency surgical procedure under general anaesthesia were randomly divided into two groups A & B. A rapid sequence induction and intubation were done in all the patients. Group a patients received 0.6mg/kg rocuronium and Group B received 1.5mg/kg succinylcholine. Intubation was done at 60 seconds after the administration of muscle relaxant and intubating conditions was graded according to Copenhagen Consensus Conference Rating Scale. The haemodynamic parameters (pulse rate& blood pressure) were recorded and compared. Results: In both the groups pulse rate and blood pressure increases significantly just after intubation but the increase was not significant after 10 minutes. There was no significant difference regarding laryngoscopy, vocal cord relaxation and response to intubation in both the groups. Overall intubating conditions in group A and B were excellent in 77.5% and 82.5% while good in 20% and17.5% patients respectively. Only one patient (2.5%) in group A showed poor intubating condition. Clinically acceptable intubating conditions (excellent & good) were comparable in both the groups. Conclusion: Rocuronium 0.6mg/kg provides clinically acceptable intubating conditions similar to succinylcholine 1.5mg/kg at 60 second during rapid sequence induction and intubation with minimum haemodynamic variations.
Authors and Affiliations
Dr Ibemhal Heisnam
Keywords
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