A COMPARATIVE STUDY OF NUTRITIONAL STATUS, GLYCEMIC STATUS AND LIPID PROFILE IN HEALTHY AND DIABETIC PATIENTS
Journal Title: International Journal of Basic and Applied Physiology - Year 2016, Vol 5, Issue 1
Abstract
Background and Objectives: Obesity is a positive risk factor in the development of type 2 diabetes mellitus, dyslipidemia, insulin resistance and hypertension. Lack of systematic study on these aspects provoked to compare the nutritional, glycemic status and lipid profile in healthy and diabetic patients. Methods: In the present study, 57 age and sex matched non-diabetic subjects, 58 diabetic only and 43 diabetic with hypertension individuals were recruited. BMI, Waist-Hip ratio, Fasting blood sugar, postprandial blood sugar, glycosylated haemoglobin (HbA1c) and lipid profile were estimated using standard procedure. The data was compared using Analysis of Variance. P value was taken as significant at 5 percent confidence level (P<0.05). Results: Analysis showed a significant increase in FBS, PPBS and HbA1c levels (p=0.001 respectively), W/H ratio (p=0.005), BMI (p=0.05) serum cholesterol and serum triglyceride levels (p=0.001) in Group-1 and Group-2 compared to controls. The HbA1c levels were higher in males of diabetic group with W/H ratio > 0.95 (p=0.001) and females of diabetic group with W/H ratio >0.80 (p= 0.001) respectively. Interpretation and Conclusion: While FBS and PPBS measurements are established guide for modifying treatment, measurement of HbA1c must be considered as a standard method for assessing longterm glycaemic control
Authors and Affiliations
K Narasimha Rai, P S Jeganathan, K M Damodara Gowda
Keywords
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