A Comparative Study of Pre Emptive Intra Muscular Phenylephrine And Ephedrine to Prevent Hypotension During Spinal Anaesthesia in Caesarean Section.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Introduction: Hypotension following spinal anaesthesia is the most common complication in patients undergoing lower segment caesarean section (LSCS). Numerous techniques have been used to prevent spinal hypotension including crystalloids, colloids and vasopressors. In this study we evaluated the effects of intra muscular phenylephrine and ephedrine in prevention of hypotension when given pre emptively 10 min prior to induction of spinal anaesthesia in patients undergoing LSCS. Material And Methods: In this study 90 ASAI and II patients assigned to undergo LSCS were randomly allocated to three groups of 30 each. Group P received intra muscular injection of Phenylephrine 100 mcg ,Group E received Inj. Ephedrine 30 mg IM and Group C received Inj. 0.9 % Normal saline 1 ml IM . Mean arterial pressure, heart rate, complications and requirement of rescue ephedrine was monitored for all patients. Results: Control of mean arterial pressure was better in Group P when compared to Group E. The rescue ephedrine requirement was found to be more in group E. On comparing the complications the incidence of nausea and vomiting was comparable in both group P and E where as tachycardia was found more in group E and bradycardia was observed more in group P. Conclusion: Pre-emptive use of both intramuscular phenylephrine and ephedrine was found to be effective in prevention of spinal anesthesia induced hypotension in patients undergoing LSCS. However, phenylephrine appears to be a better vasopressor as compared to ephedrine
Authors and Affiliations
Sushree Das, Shalini Bajpai
Keywords
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- EP ID EP239264
- DOI 10.9790/0853-1610034144
- Views 97
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