A comparative study of rebamipide 2% and carboxy methylcellulose (CMC) 0.5% eye drop in patients with dry eyes: A randomized, hospital-based study
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 4
Abstract
Aim To compare the efficacy of 2 rebamipide and 05 Carboxy methylcellulose CMC eye drops in dry eye patientsMaterials and Methods A 100 dry eye patients were enlisted and screened Patients were allotted randomly into 2 groupsGroupA 2 rebamipide or GroupB 05 Carboxy methylcellulose CMC ophthalmic solution after screening and instilled as 1 drop in each eye four times a day for about two months The signs and symptoms were assessed at baseline 2 4 and at 8week visits The objective signs were Schirmer test and Tear film breakup time TBUT while subjective symptoms were dry eye related ocular symptoms foreign body sensation dryness photophobia eye pain and blurred visionResults A compelling improvement was noticed in the Schirmer test and TBUT values after the treatment in the 2 rebamipide group The patients on 2 rebamipide eye drop showed considerable improvement in dry eye related ocular symptoms than the patients on 05 CMC eye drop 51 and 29 respectively at 2 monthsConclusions 2 rebamipide ophthalmic solution was more efficient in improving both the subjective symptoms and objective signs of dry eye in comparison to the CMC group in this 8week study These findings showed that 2 rebamipide is the more effective drug for dry eye Keywords Carboxy methylcellulose Dry eye Efficacy Rebamipide
Authors and Affiliations
Palvee Menon, Dipak B. Patel, Anshi Rathod, Aneesha Vyas, Poonam Rana
Keywords
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- EP ID EP474869
- DOI 10.18231/2395-1451.2018.0118
- Views 51
- Downloads 0
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