A comparative study of serum lipoprotein ‘a’ [S(Lp(a)] in type - II diabetic v/s nondiabetic patients with ST-Elevation Myocardial Infarction (STEMI)
Journal Title: MedPulse -International Medical Journal - Year 2018, Vol 5, Issue 4
Abstract
Aim: The study was aimed to compare the serum levels of Lp(a) in between diabetic and Nondiabetic patients who presented with STEMI and to study the correlation if any between dyslipoprotien(a)emia and dyslipidemia in patients with acute STEMI(Diabetics and Nondiabetics). Methods: All individuals with established DM-2 along with acute STEMI and without any major overt complication were recruited from cardiology outdoor, medical outdoor and indoor for the study. The subjects were of middle and elderly age group. Complete history and comprehensive clinical examination along with all the planned investigations were alone. Each subject was investigated for glycaemic status, ECG changes, lipid profile and Lp(a) estimation. Results: The S.Lp(a) level were higher in nondiabetic group(36.18±19.96 mg/dl) compared to diabetic group(31.53±8.39 mg/dl) but the difference was not statistically significant(p>0.1). Also the lipid profile of these patients was deranged and there was a fair correlation between lipid variables and Lp(a). Conclusion: The prevalence of dyslipidemia and dyslipoprotein(a)emia is very high in those presenting with acute STEMI. All lipid variables were found to be raised except HDL along with S.Lp(a), which was found to be higher in nondiabetic patients compared to diabetics in acute STEMI but the values were significantly higher then the normal values.
Authors and Affiliations
Puneet Nag, Anshu Mathur, Ram Ratan Yadav
Keywords
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