Histopathological evaluation of endoscopic biopsy specimens of ulcerative colitis
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 4
Abstract
Background: Nonneoplastic colorectal diseases including non specific colitis and ulcerative colitis are very common diseases all over the world and account for major portion of the gastrointestinal morbidity. Histopathological study of endoscopic colorectal biopsy plays a major role in the diagnosis of these diseases. Scoring of ulcerative colitis further establishes its role in the prognosis and helps clinicians in efficient patient management. Methodology: This is a prospective study of 33 patients who underwent endoscopic colorectal biopsies in various hospitals in and around Mangaluru and in Yenepoya Medical College and hospital, Mangaluru from October 2013 to September 2015. Histopathological diagnosis was made in each case in cases of ulcerative colitis scoring was done by K. Geboes scoring system. Results: Among the 33 cases studied of ulcerative colitis, twenty two (66.66%) were males (n=22) and eleven (33.33%) were females (n=11) with a ratio of 2:1. This indicates the male preponderance of ulcerative colitis. Ulcerative colitis cases were classified according to the Montreal classification. Maximum number of patients with ulcerative. colitis were in the age group of 56-65 years. Ulcerative colitis was more common among men compared to women (M: F=2:1). Ulcerative colitis cases were graded according to K. Geboes grading system. Most of the cases were in grade 4 and 5. Conclusion: Histopathological examination of endoscopic colorectal biopsies is a very useful tool in the accurate diagnosis of non-neoplastic colorectal diseases and excluding neoplastic diseases especially colorectal cancer.
Authors and Affiliations
Namrata Sharan Sinha, Krishnaraj Upadhyaya
Keywords
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